Pharmaceutical Forensics
The need for identification of counterfeit pharmaceuticals is becoming increasingly important. The presentations in this Tuesday morning session will examine various techniques of analyzing counterfeit drugs and packaging.
The need for identification of counterfeit pharmaceuticals is becoming increasingly important. The presentations in this Tuesday morning session will examine various techniques of analyzing counterfeit drugs and packaging.
The first presentation in the session will be delivered by Anthony Zook of Merck and Co., Inc., and is titled “Analysis of Suspected Counterfeit Drugs: Application of Emerging Analytical Methods.” Zook’s talk will discuss the use of direct analysis in real time (DART) mass spectrometry for rapid analysis of counterfeit pharmaceutical products.
Zook’s presentation will be followed by a talk delivered by Robert Brush of Ahura Scientific. The presentation, titled “Authentication of Pharmaceutical Products by Fieldable Raman Spectroscopy,” will cover the use of a portable Raman authentication system to detect counterfeit pharmaceutical products.
The next presentation, titled “Multivariate Analysis of ATR-FTIR Spectroscopic Data for the Forensic Examination of Pharmaceutical Labels,” will be presented by Mary Carrabba of Southern Oregon University. She will talk about the characterization and discrimination of paper-backed, pressure-sensitive adhesive labels as a means to identify counterfeit pharmaceutical packaging.
Mark Witkowski of the FDA Forensic Chemistry Center will discuss the various techniques used by the Forensic Chemistry Center’s Trace Examination Section to examine samples for trace evidence as part of pharmaceutical forensic cases. The title of his presentation is “Trace Examination Techniques and Their Use in Pharmaceutical Forensics.”
The final two presentations in the session will be delivered by Jean-Claude Wolff of GlaxoSmithKline. The first, titled “Comparison of LC/MS and Ion Mobility Spectrometry Combined with Mass Spectrometry for the Differentiation of Counterfeit Heptodin,” will discuss the use of ion mobility spectrometry (IMS) combined with mass spectrometry (MS) versus liquid chromatography (LC)–MS and LC–IMS-MS for the identification and differentiation of various counterfeit samples of an antihepatitis drug. His second presentation, the final one in the session, titled “Carbon, Magnesium, and Sulfur Isotope Ratio Measurements Combined with Trace Metal Profiling for Detection of Counterfeit Antiviral Drugs,” covers isotopic fingerprinting and trace metal profiling techniques used to identify a suspected counterfeit antiviral drug.
Getting accurate IR spectra on monolayer of molecules
April 18th 2024Creating uniform and repeatable monolayers is incredibly important for both scientific pursuits as well as the manufacturing of products in semiconductor, biotechnology, and. other industries. However, measuring monolayers and functionalized surfaces directly is. difficult, and many rely on a variety of characterization techniques that when used together can provide some degree of confidence. By combining non-contact atomic force microscopy (AFM) and IR spectroscopy, IR PiFM provides sensitive and accurate analysis of sub-monolayer of molecules without the concern of tip-sample cross contamination. Dr. Sung Park, Molecular Vista, joined Spectroscopy to provide insights on how IR PiFM can acquire IR signature of monolayer films due to its unique implementation.
Researchers Develop Adaptive Gap-Tunable SERS Device
April 24th 2024In a new study, researchers from Ulsan National Institute of Science and Technology and Pohang University of Science and Technology presented a new surface-enhanced Raman spectroscopy (SERS) device, improving gap plasmon resonance.
