Bruce Laprade

Bruce Laprade is director of engineering at Burle Electro-Optics in Sturbridge, Massachusetts.


Time-of-Flight Mass Spectrometry for Proteomics Research

May 02, 2005

Time-of-Flight (TOF) is rapidly becoming the most popular method of mass separation for proteomics and conventional analytical chemistry. The development of very high temporal resolution ion detectors and low-cost high-speed digitizers has rendered this technique easily deployed and able to produce very high mass resolution. The performance of a TOF mass spectrometer is dependent upon a number of critical components. This article will focus on the ion detector.