Michael P. Balogh

The authors discuss the changes that have taken place in the last two decades regarding the users and capabilities of LC–MS.

This article provides an overview of several recently developed technologies that will improve the utility and performance of mass spectrometers in a number of applications.

The authors discuss current approaches for increasing throughput in MS analyses, including improved software information flow, data management and effective sample preparation, and how researchers should consider each of these with regard to their own needs.

When considering accurate mass and greater resolution, which mass spectrometer provides the information needed at the best purchase price and with the most accessible operational prospects?

The author discusses how the physical realm of the atmospheric ionization source -- materials, gas, and heat dynamics -- and manipulating the ionization modes themselves perhaps are the current forefront of technological innovation.

A preview of this year's 50th American Society of Mass Spectrometry (ASMS) Conference on Mass Spectrometry and Allied Topics in Orlando, June 2-6, 2002.