Analyzing Carbohydrates on Therapeutic Glycoproteins
Spectroscopy E-Books
A very important component of the characterization of therapeutic proteins is the analysis of the carbohydrate structures that are attached to them. Those carbohydrates play an important role in ensuring the safety and efficacy of these drugs, and are an important consideration when comparing a candidate biosimilar drug to its reference product. For advice on this topic,
LCGC
spoke to Parastoo Azadi, PhD, the technical director for analytical services at the University of Georgia Complex Carbohydrate Research Center. Read more
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Getting accurate IR spectra on monolayer of molecules
April 18th 2024Creating uniform and repeatable monolayers is incredibly important for both scientific pursuits as well as the manufacturing of products in semiconductor, biotechnology, and. other industries. However, measuring monolayers and functionalized surfaces directly is. difficult, and many rely on a variety of characterization techniques that when used together can provide some degree of confidence. By combining non-contact atomic force microscopy (AFM) and IR spectroscopy, IR PiFM provides sensitive and accurate analysis of sub-monolayer of molecules without the concern of tip-sample cross contamination. Dr. Sung Park, Molecular Vista, joined Spectroscopy to provide insights on how IR PiFM can acquire IR signature of monolayer films due to its unique implementation.
