Manufacturing control of pharmaceutical solids requires routine measurement of content uniformity. Because of the high information content in Raman spectra, it has been considered a candidate technology for making these measurements.
Compounds of magnesium and calcium are common components of pharmaceutical formulations. Spectroscopic imaging can provide a complete understanding of a formulation. This paper compares two spectral imaging techniques — energy dispersive X-ray fluorescence (EDXRF) microscopy and Raman microscopy.