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Density Functional Model of Raman Spectra for the Seminiferous Tubules of Hindlimb Unloaded MiceThis study examines whether the computed spectrum can be used to accurately identify amino acids, by comparing the computer spectrum to the measured spectrum of a biological sample.
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Strategies for Analyzing Challenging Samples: Fusion for ICP & XRF Sample PrepWebinar Date/Time: Wed, Nov 20, 2024 2:00 PM EST
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Authenticity Identification of Panax notoginseng by Terahertz Spectroscopy Combined with LS-SVMIn this article, it is explored whether THz-TDS combined with LS-SVM can be used to effectively identify the authenticity of Panax notoginseng, a traditional Chinese medicine.
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Authenticity Identification of Panax notoginseng by Terahertz Spectroscopy Combined with LS-SVMIn this article, it is explored whether THz-TDS combined with LS-SVM can be used to effectively identify the authenticity of Panax notoginseng, a traditional Chinese medicine.
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Challenges of Spectrofluorometry, Part 1: Collect Data Right the First TimeAnalysts using fluorescence emission and fluorescence excitation spectroscopy may encounter several common problems in their measurements. This tutorial, the first of a three-part series, provides a procedure to help avoid them.
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Quantum Computer Helium Laboratory Oxygen Deficiency MonitorThis application note demonstrates the performance of the Oxigraf Safety Monitor to measure the concentration of oxygen molecules in gas samples at a helium laboratory.
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Fiberoptic Formaldehyde Field Sensors for Industrial Environments: Capitalizing on Evanescent-Wave SpectroscopyAn inexpensive fiberoptic-based formaldehyde field sensor is described for monitoring low-levels of formaldehyde, a widespread indoor air pollutant, based on the principle of evanescent wave absorption of light. Sensor prototypes following that principle are being tested in two plywood board production plants.
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A Novel High Selectivity Fluorimetric and Colorimetric Probe Based on Rhodamine B Hydrazide Derivatives for Detecting Hg2+ in Aqueous MediaA simple colorimetric and fluorescent dual-channel chemosensor was designed and synthesized to identify Hg2+ in an aqueous solution with demonstrated high selectivity and sensitivity.
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Evaluation and Development Trends of Optical Detection Technology for Seed VigorIn this article, the basic principles, advantages, and limitations of different optical techniques for obtaining seed vigor estimates are introduced and reviewed, and the key technology of non-destructive optical detection of single seeds will be discussed.
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Characterization of GeSbSe Thin Films Synthesized by the Conventional Melt-Quenching MethodSpectroscopic ellipsometry, correlated with UV-vis-NIR spectroscopy, is used to determine the optical constants of thin films, such as in GexSb40-xSe60 chalcogenide glass.
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Analysis of Serum from Acute Leukemia Patients Using Surface-Enhanced Raman Spectroscopy (SERS)This study shows that surface-enhanced Raman spectroscopy (SERS) of serum can provide an experimental basis for diagnosing leukemia in patients.
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Interacting Characteristics of Chrysene with Free DNA in vitroDNA effectively removes chrysene from contaminated water through intercalation, as confirmed by various analytical methods, offering a potential novel approach for chrysene elimination in water pollution.
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Hyperspectral Imaging Combined with Convolutional Neural Network for Rapid and Accurate Evaluation of Tilapia Fillet FreshnessThe purpose of this work is to achieve rapid and nondestructive determination of tilapia fillets storage time associated with its freshness. Here, we investigated the potential of hyperspectral imaging (HSI) combined with a convolutional neural network (CNN) in the visible and near-infrared region (vis-NIR or VNIR, 397−1003 nm) and the shortwave near-infrared region (SWNIR or SWIR, 935−1720 nm) for determining tilapia fillets freshness.
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2025 Review of Spectroscopic InstrumentationThis product review covers products introduced from May 2024 to April 2025.
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Using Information-Based Classifications to Distinguish Characteristics of Raw Agricultural Materials by Near-Infrared SpectroscopyTraditional qualitative analysis of agricultural materials using near-infrared spectroscopy can be improved using information-based classification methods, such as projection based on principal components and the Fisher criterion (PPF).
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In Situ Enhancement of Microplastic Raman Signals in Water Using Ultrasonic CaptureOf the 78 million tons of plastic packaging manufactured every year, approximately one-third ends up in the ocean, the air, and most foods and beverages. To monitor the proliferation of these plastics, an ultrasonic capture method is demonstrated that produces a 1500-fold enhancement of Raman signals of microplastics in water.
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An Archaeometric Investigation into the Former Cataract House Hotel via Elemental AnalysisPortable X-ray fluorescence was used to analyze the archaeological remains of an Underground Railroad station to gain a clearer understanding of the construction phases it underwent during the 19th century.
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Porous Chitosan Composite Membrane Tandem Laser-Induced Breakdown Spectroscopy for Detection of Metal Elements in Liquid SamplesDetecting metal elements in liquid samples cannot be done efficiently by only using LIBS, but when the technique is combined with appropriate membrane materials, rapid analysis of solution samples can be realized.
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A Fingerprint in a Fingerprint: Raman Spectral Analysis of Pharmaceutical IngredientsThe significance of the smaller spectral region of the Raman spectrum, defined as the “fingerprint in the fingerprint” region, cannot be overstated when it comes to active pharmaceutical ingredient identity testing (API).
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Quo Vadis Analytical Procedure Development and Validation?A look at two ICH draft publications reveals that the EWG has much revision work to do for these publications to fully cover the validation lifecycle process.
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Solid Physical State Transformation in Hot Melt Extrusion Revealed by Inline Near-Infrared (NIR) Spectroscopy and Offline Terahertz (THz) Raman ImagingInline FT-NIR and offline terahertz Raman imaging analysis are used to characterize active pharmaceutical ingredient (API) crystallinity and to monitor different solid physical states of the API, to control process parameters of hot melt extrusion.
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Geographical Traceability of Millet by Mid-Infrared Spectroscopy and Feature ExtractionThe study developed an effective mid-infrared spectroscopic identification model, combining principal component analysis (PCA) and support vector machine (SVM), to accurately determine the geographical origin of five types of millet with a recognition accuracy of up to 99.2% for the training set and 98.3% for the prediction set.
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Tracking Photocuring via ATR-FT-IR with Illumination through the ATR ElementThe utility of the GladiATR diamond ATR, modified with an internal liquid light guide to illuminate the sample from underneath the ATR element, was explored to analyze the photo-polymerization of carbitol acrylate at 405 nm using 1 wt% TPO.
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Optical Measurement of the Reflectance Behavior of Z93, the Thermal Coating on the International Space StationMeasurements of the optical proper ties of a ceramic material, Z93, which is in current use on the International Space Station (ISS), reveal why this material is successful for thermal control in the ISS implementation, and also point to potential future material design improvements.
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Aggregate and Fragment Analysis in Therapeutic Monoclonal Antibodies Using On-Line Size-Exclusion Chromatography with Native Mass SpectrometrySize-exclusion chromatography (SEC), with the use of ammonium acetate buffer, can be coupled on-line to electrospray ionization MS for the characterization of size variants of therapeutic monoclonal antibodies (mAbs). A quadrupole time-of-flight (QTOF) MS system was employed, and the MS method was optimized to achieve favorable sensitivity for high-mass detection, while maintaining the structural integrity of the aggregates (or high molecular weight species) and fragments (or low molecular weight species).
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Measurement of Ammonia Leakage by TDLAS in Mid-Infrared Combined with an EMD-SG Filter MethodIn this article, tunable diode laser absorption spectroscopy (TDLAS) is used to measure ammonia leakage, where a new denoising method combining empirical mode decomposition with the Savitzky-Golay smoothing algorithm (EMD-SG) is proposed to improve the signal-to-noise ratio (SNR) of absorbance signals.
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High-Throughput Profiling of Long Chain Fatty Acids and Oxylipins by LC–MSLong chain fatty acids (LCFAs) function as a source of metabolic energy, substrates for membrane biogenesis, and storage of metabolic energy. Oxylipins, oxygenated derivatives of LCFAs, regulate the activity of many cellular processes. Existing methods for the analysis of LCFAs and oxylipins have limited compound coverage and sensitivity that, therefore, prevent their application in biological studies. In this work, we developed a high-throughput LC–MS method for analysis of 51 LCFAs and oxylipins. LCFAs and oxylipins were first extracted from biological samples via solid-phase extraction. The extracted molecules were analyzed by targeted comparative metabolomics. Saturated and monounsaturated LCFAs were analyzed in single ion reaction mode, while polyunsaturated LCFAs and oxylipins were analyzed in multiple reaction monitoring mode. Using this method, we successfully quantified 31 LCFAs and oxylipins from mouse livers.
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Polychromatic and Microfocused X-ray Radiation for Traceable Quantitative X-ray Fluorescence AnalysisIn X-ray fluorescence (XRF) analysis, physical traceability chains are used to quantify the absolute elemental content in a sample. The physical traceability chain relies on absolute knowledge of the X-ray spectral distribution used for the excitation of the instrument and is currently used at synchrotron radiation facilities. Here, we discuss the transfer of the physical traceability chain to laboratory-based X-ray sources, which are often polychromatic, with the view to generate wider application of quantitative XRF analysis.
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In situ Raman Spectroscopy Monitors the Corrosion of Mild Steel in a Salt Fog ChamberIn this study, in situ Raman spectroscopy was used to detect the formation, growth, and evolution of corrosion inside a salt fog chamber. These results pave the way for monitoring the real-time observation of corrosion on metal surfaces.
