The Eastern Analytical Symposium (EAS) Award for Outstanding Achievements in Mass Spectrometry will be presented to Barbara Larsen.
The Eastern Analytical Symposium (EAS) Award for Outstanding Achievements in Mass Spectrometry will be presented to Barbara Larsen on Thursday, November 19 at the EAS Virtual Symposium.
Barbara Larsen, PHD
Barbara Larsen is a Nutrition and Biosciences fellow at the DuPont Experimental Station in Wilmington, Delaware. Her research focuses on the application of mass spectrometry to support the biotechnology business. She has a keen interest in ionization methods to ensure the continued relevance of mass spectrometry for biotechnology projects at DuPont. Larsen has a passion for fitness for purpose—selecting the best measurement technology to provide the critical solution to a specific problem. For her work supporting biotechnology research, Larsen has developed a digestion protocol for bioproteins that provides coverage of the expressed protein sequence or deep proteomic coverage of the organism that produced the protein. In addition, these methods can be used to provide details on protein modifications that occur during host expression or during processing. Her research interests include using a systems biology approach including metabolomics, proteomics, and transcriptomics to improve enzyme production and probiotic organisms.
Larsen has been part of the DuPont Company for the past 35 years. She received her BS from the University of Santa Clara, California, and her PhD in Physical Chemistry at the University of Delaware, followed by a post-doctoral fellowship at Johns Hopkins School of Medicine. Larsen has received the Spectroscopy Society Award and the Delaware ACS Section Research Award. DuPont awarded her research with the Pederson Award, for significant scientific achievement that reflects technical excellence.
She is currently a member of American Society of Mass Spectrometry—where she has served as the treasurer, vice president of programs, and president—and is on the advisory board for the society journal. As an active member of the American Chemical Society (ACS), she was made an ACS fellow for her service as the chair for the Delaware Valley Mass Spectrometry Discussion Group and as a counselor for the Delaware ACS section. She also serves on the editorial advisory board of Spectroscopy.
Getting accurate IR spectra on monolayer of molecules
April 18th 2024Creating uniform and repeatable monolayers is incredibly important for both scientific pursuits as well as the manufacturing of products in semiconductor, biotechnology, and. other industries. However, measuring monolayers and functionalized surfaces directly is. difficult, and many rely on a variety of characterization techniques that when used together can provide some degree of confidence. By combining non-contact atomic force microscopy (AFM) and IR spectroscopy, IR PiFM provides sensitive and accurate analysis of sub-monolayer of molecules without the concern of tip-sample cross contamination. Dr. Sung Park, Molecular Vista, joined Spectroscopy to provide insights on how IR PiFM can acquire IR signature of monolayer films due to its unique implementation.