Author | Jason D. Keith

Articles

Microwave Digestion of Pharmaceutical Samples for USP Method

February 01, 2013

Application Notebook

Article

Pharmaceutical samples spiked with several heavy metals were prepared for ICP-MS analysis using microwave digestion following the protocols in proposed USP chapters and . The results of the spike recovery study are discussed.

Microwave Digestion of Pharmaceutical Finished Products and Ingredients for Upcoming USP Method 233

February 01, 2012

Application Notebook

Article

Current USP Method 231 "Heavy Metals" was introduced in 1905 for determining heavy metal impurities in pharmaceutical drug products. The procedures of the method have several limitations, which produce results that are nondiscriminatory, difficult to reproduce, and qualitative, or at best, semi-quantitative.