Author | Melissa Churley

Articles

Ultralow Detection of Estrogenic Compounds by GC–NCI-MS-MS

May 01, 2010

Special Issues

Article

A number of clinical situations now call for high-sensitivity measurement of estrogens, including monitoring during female hormone replacement therapy, antiestrogen treatment, and estrogen deficiency in men. Traditional immunoassay methods and liquid chromatography–tandem mass spectrometry (LC–MS-MS) do not provide the sensitivity and selectivity required for these applications. In contrast, a gas chromatography–negative chemical ionization–tandem mass spectrometry (GC–NCI-MS-MS) platform can provide detection limits below 1 pg/mL when used in conjunction with the appropriate derivatization protocol, with very short cycle times.

The Role of Triple Quadrupole GC–MS in Steroid Analysis

May 01, 2009

Special Issues

Article

The authors discuss the use of GC-MS in drug doping testing.

Comprehensive Screening, Confirmation, and Quantification of Organic Pesticides in Foods by GC–MS and LC–MS

November 01, 2008

Special Issues

Article

This article provides an overview of the instrument platforms, tools, and workflow for analyzing pesticides.