April/May 2025

Molecule of an amide with a nucleophile attacking the carbonyl group. Generated by AI. | Image Credit: © udomsak - stock.adobe.com.

Carbonyl containing functional groups are strong infrared absorbers and a number of them are easy to identify by infrared spectroscopy. Here, we will review the spectra of ketone and carboxylic acids.

Fuel processing control room with a comprehensive digital interface system. Generated with AI. | Image Credit: © Srinard - stock.adobe.com.

United States Pharmacopoeia (USP) general chapter <1058> on Analytical Instrument Qualification (AIQ) now has a new title from a draft update for public comment: Analytical Instrument and System Qualification (AISQ). A new three-phase integrated lifecycle phase approach to qualification and validation is described. But will laboratories and suppliers implement it?

C. V. Raman in 1930

In this "Icons of Spectroscopy" column, executive editor Jerome Workman Jr. delves into Part I of the life and work of C. V. Raman, a physicist who has made major contributions to the science of vibrational spectroscopy and created an understanding for one of the most important quantum-based spectroscopy tools in generations.

Refrigerator room. Factory style cold room ice. Generative AI. | Image Credit: © Aiakos - stock.adobe.com.

In this article, tunable diode laser absorption spectroscopy (TDLAS) is used to measure ammonia leakage, where a new denoising method combining empirical mode decomposition with the Savitzky-Golay smoothing algorithm (EMD-SG) is proposed to improve the signal-to-noise ratio (SNR) of absorbance signals.