Atomic spectroscopy has quietly gone from counting elements in bulk to counting single nanoparticles, imaging tissue at the micrometer scale, and reading Martian rocks from several meters away. The instruments got smaller, the software got smarter, and the questions they can now answer got a lot more interesting.

How do ions and water interact at the atomic level in nanochannels grafted with polymer brushes using all-atom molecular dynamics simulations? Siddhartha Das of the University of Maryland and his team are working on answering this question.

Mammograms can find breast microcalcifications but can’t tell whether they are likely benign or malignant.

In a SciX interview, Marc Porter covered a lot of ground, from a student-driven pivot into immunoassays to a baseball analogy for Stokes and anti-Stokes scattering, and shares the open questions he is still chasing.

Laser-induced breakdown spectroscopy (LIBS) is being used in numerous application areas, including environmental monitoring, cultural heritage, and space exploration.

At SciX, Kevin Wilkinson of the Universite de Montreal explains how faster data acquisition and new software have cut analysis time and how a particle’s chemical composition can link arsenic-bearing emissions back to a copper refinery’s processes.

Microspectroscopy, the marriage of spectroscopic chemical identification with microscopic spatial resolution, has advanced from Perkin-Elmer's first commercial infrared microspectrometer in 1953 to today's nanoscale AFM-IR probes, synchrotron-brightness infrared beamlines, and compact hyperspectral tissue imaging devices being developed for AI-assisted cancer detection.

Marc Porter describes how his group’s surface science work led to SERS-based immunoassays, why reproducibility and pre-analytics decide whether a test reaches the clinic, and the questions he still wants to answer.