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Christoph Gstöttner

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Articles

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Rapid Online Reduction and Characterization of Protein Modifications Using Fully Automated Two-Dimensional High Performance Liquid Chromatography–Mass Spectrometry

Denis Klemm;Christoph Gstöttner;Anja Bathke;Robert Kopf;Christian Bell
March 1st 2018

A fully automated process for online peak fractionation and reduction of therapeutic antibodies with subsequent QTOF-MS characterization is presented. The technique is based on state-of-the-art 2D-HPLC technology coupled with additional HPLC modules via a dedicated software macro.

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