Author | Kirsten Hobby

Kirsten Hobby is with Waters Corporation.

Articles

An Expanding Role: The Use of Ultrahigh Performance LC–TOF-MS, GC–TOF-MS, Accurate Mass, and Isotope Modeling for Screening Complex Mixtures

November 01, 2006

Special Issues

Article

Ultrahigh performance liquid chromatography (LC)–time-of-flight mass spectrometry –(TOF-MS) and gas chromatography (GC)–TOF-MS are powerful approaches for screening target compounds and identifying or characterizing nontarget compounds in complex mixtures. The combination of accurate mass data and newly developed software enables truly generic screening methods with TOF-MS, and the confident detection, identification, and confirmation of small molecules in a range of application areas.