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Latest:
Single-Cell ICP-MS Analysis: Quantifying the Metal Concentration of Unicellular Organisms at the Cellular LevelSingle-cell ICP-MS can accurately quantify the metal concentrations within individual cells, providing new information about the mean metal content and the variation within a cell population. This method is shown to be a vital tool for assessing the specific uptake of metals by ovarian cancer cells and fresh water algae.
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Single-Cell ICP-MS Analysis: Quantifying the Metal Concentration of Unicellular Organisms at the Cellular LevelSingle-cell ICP-MS can accurately quantify the metal concentrations within individual cells, providing new information about the mean metal content and the variation within a cell population. This method is shown to be a vital tool for assessing the specific uptake of metals by ovarian cancer cells and fresh water algae.
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The Evolving Role of Contract Manufacturing in Semiconductor ManufacturingExperts explore the evolving role of CDMOs in semiconductor fabrication and why strategic partnerships are increasingly critical for process innovation and cost control.
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Solid Physical State Transformation in Hot Melt Extrusion Revealed by Inline Near-Infrared (NIR) Spectroscopy and Offline Terahertz (THz) Raman ImagingInline FT-NIR and offline terahertz Raman imaging analysis are used to characterize active pharmaceutical ingredient (API) crystallinity and to monitor different solid physical states of the API, to control process parameters of hot melt extrusion.
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Exploring the Unknown with Correlative Raman Imaging and Scanning Electron MicroscopyConfocal Raman imaging and scanning electron microscopy are techniques that are ideally suited to correlating structural and chemical information as shown here on a variety of samples.
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Data-Driven Raman Spectroscopy in Oil and Gas: Rapid Online Analysis of Complex Gas MixturesThis new data-driven Raman spectroscopy (DDRS) method is capable of simultaneously measuring 12 hydrocarbon and nonhydrocarbon gases in the presence of matrix interferences.
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Exploring the Unknown with Correlative Raman Imaging and Scanning Electron MicroscopyConfocal Raman imaging and scanning electron microscopy are techniques that are ideally suited to correlating structural and chemical information as shown here on a variety of samples.
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Exploring the Unknown with Correlative Raman Imaging and Scanning Electron MicroscopyConfocal Raman imaging and scanning electron microscopy are techniques that are ideally suited to correlating structural and chemical information as shown here on a variety of samples.
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Lithium-Ion Battery Analysis: A Virtual SymposiumWebinar Date/Time: Thursday, September 26, 2024 Morning Session: 10:00 AM EDT | 7:00 AM PDT | 3:00 PM BST | 4:00 PM CEST Afternoon Sesson: 12:30 PM EDT | 9:30 AM PDT | 5:30 PM BST | 6:30 PM CEST
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Evaluation of Modified QuEChERS for Pesticide Analysis in CannabisWell-established techniques used by the food safety industry, such as QuEChERS sample preparation followed by LC–MS/MS for the analysis of multiresidue pesticides, are evaluated for use with cannabis plant material.We evaluated a modified QuEChERS LC-MS/MS method for analysis of multiresidue pesticides.
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Target Anode Material for HHXRF InstrumentsThis application note provides insights for the proper selection of anode materials and thicknesses for HHXRF applications.
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Native Measurement of a Biotherapeutic without Interference from Excipients Using Microfluidic Modulation SpectroscopyA new infrared spectroscopy technique, microfluidic modulation spectroscopy (MMS), delivers reproducible protein characterization over close to four orders of magnitude in protein concentration (from 0.1 to 200 mg/mL). This technique characterizes samples from the earliest stages of development through to manufacture.
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Direct Determination of Oil Content in Binary Mixtures of Peanut and Canola Oils Using Partial Least Squares and Attenuated Total Reflectance Fourier Transform Infrared SpectroscopyThis study presents a novel, time-efficient, and cost-effective procedure for determining the percentage of oil content in binary mixtures of peanut and canola oils.
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Direct Determination of Oil Content in Binary Mixtures of Peanut and Canola Oils Using Partial Least Squares and Attenuated Total Reflectance Fourier Transform Infrared SpectroscopyThis study presents a novel, time-efficient, and cost-effective procedure for determining the percentage of oil content in binary mixtures of peanut and canola oils.
Latest:
Direct Determination of Oil Content in Binary Mixtures of Peanut and Canola Oils Using Partial Least Squares and Attenuated Total Reflectance Fourier Transform Infrared SpectroscopyThis study presents a novel, time-efficient, and cost-effective procedure for determining the percentage of oil content in binary mixtures of peanut and canola oils.
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Enhanced Protein Structural Characterization Using Microfluidic Modulation SpectroscopyThis article introduces a new infrared (IR) technique, microfluidic modulation spectroscopy (MMS), that is designed to address these needs, and presents data from measurements of commercially available proteins. The data demonstrate significant increases in sensitivity, dynamic range, and utility for the determination of protein similarity (fingerprinting), quantitation, protein secondary structure, and protein stability and aggregation through thermal and chemical denaturation methods.
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Enhanced Protein Structural Characterization Using Microfluidic Modulation SpectroscopyThis article introduces a new infrared (IR) technique, microfluidic modulation spectroscopy (MMS), that is designed to address these needs, and presents data from measurements of commercially available proteins. The data demonstrate significant increases in sensitivity, dynamic range, and utility for the determination of protein similarity (fingerprinting), quantitation, protein secondary structure, and protein stability and aggregation through thermal and chemical denaturation methods.
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Fast Quality Evaluation of Bulk Polymers and Products Using FT-NIR SpectroscopyFT-NIR spectroscopy for the quantitative determination of key physical parameters in bulk polymers and products, including density and melt index (MI). These measurements can often be made with little or no sample preparation.
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Spectroscopy Guides Long-Term Conservation of Renaissance Murals in ValenciaResearchers at the University of the Basque Country, along with Català Restauradors S.L. analyzed the emergence of soluble salts on mural paintings in the vault of the Valencia Cathedral, using Raman and micro-energy-dispersive X-ray fluorescence spectroscopy combined with ion chromatography.
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DNA Adductomic Analysis by Data-Independent Mass SpectrometryA new type of analysis called “wide-selected ion monitoring (SIM)/MS2” scanning, is capable of screening for a wide range of DNA adducts (chemical modifications to genomic DNA). This method has successfully identified DNA adducts from carcinogen exposures and oxidative stress in human prostate and kidney tissues.
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DNA Adductomic Analysis by Data-Independent Mass SpectrometryA new type of analysis called “wide-selected ion monitoring (SIM)/MS2” scanning, is capable of screening for a wide range of DNA adducts (chemical modifications to genomic DNA). This method has successfully identified DNA adducts from carcinogen exposures and oxidative stress in human prostate and kidney tissues.
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DNA Adductomic Analysis by Data-Independent Mass SpectrometryA new type of analysis called “wide-selected ion monitoring (SIM)/MS2” scanning, is capable of screening for a wide range of DNA adducts (chemical modifications to genomic DNA). This method has successfully identified DNA adducts from carcinogen exposures and oxidative stress in human prostate and kidney tissues.
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Targeted Metabolomics Analysis of Type 2 Diabetes Serum Samples Using Mass Spectrometry and a Standardized Quantitative MethodAn important advantage of standardized methods is that they enable comparability between laboratories and across studies. In this work, the author used a standardized targeted kit to demonstrate the accuracy, sensitivity, and reproducibility of the approach, analyzing serum samples obtained from type 2 diabetes study subjects and healthy controls.
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Review of the 66th Conference on Mass Spectrometry and Allied TopicsOur annual review of the ASMS national conference. This year’s event was held June 3–7 in San Diego, California.
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Rapid Classification of Beef Aroma Quality Using SIFT-MSApplication of multivariate statistical analysis to a combined data set demonstrated that SIFT-MS discriminates premium quality beef from eight sensory defects, and, therefore, could be applied as an instrumental grading tool, obviating sensory panel grading.
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Rapid Classification of Beef Aroma Quality Using SIFT-MSApplication of multivariate statistical analysis to a combined data set demonstrated that SIFT-MS discriminates premium quality beef from eight sensory defects, and, therefore, could be applied as an instrumental grading tool, obviating sensory panel grading.
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High-Throughput Analysis of Volatile Compounds in Air, Water, and Soil Using SIFT-MSFor the BTEX compounds, detection limits in the single-digit parts-per-billion concentration range (by volume) are readily achievable within seconds using selected ion flow tube mass spectrometry (SIFT-MS), because sample analysis is achieved without chromatography, preconcentration, or drying.
