At SciX, Jay Kitt describes the experiment he ran on his own that launched his cytochrome c research, and explains why putting a number on peptide–lipid interactions matters.

Jürgen Popp explains how head and neck surgeons in Jena use a Raman probe to locate tumor borders, why the technique could replace frozen section biopsies, and why optical tools must adapt to clinical workflows rather than the other way around.

At SciX, Juergen Popp explains why a new infection test must fit hospital workflows, outperform the gold standard, and cost about a euro or less per test. He also describes a host-response test that could change how emergency departments treat suspected sepsis.

Jay Kitt of the University of Utah explains that his group’s platform for quantitative Raman measurements inside chromatographic particles didn’t come from a search for signal enhancement. It grew out of a decade of chromatography and biochemistry research.

The inaugural Peter Griffiths Award winner discusses deep low-frequency Raman measurements through wax and what remains before clinical breast-imaging use.

The recipient of the ACS Award in Spectrochemical Analysis discusses how surface-enhanced Raman scattering became a practical diagnostic readout and how close it is to clinical use.

The 2026 Ellis R. Lippincott Award recipient discusses the barriers to clinical adoption of photonic diagnostics and his vision for personalized optical digital twins.

Wednesday's program at SciX 2026 kept returning to one question: can spectroscopy perform outside the controlled laboratory? Speakers took surface-enhanced Raman scattering (SERS), laser-induced breakdown spectroscopy (LIBS), mid-infrared photonics, chemometrics, and fluorescence excitation–emission matrix (EEM) spectroscopy into clinics, food plants, reactor coolant loops, brine fields, and drinking water supplies.