Surface-enhanced Raman spectroscopy (SERS)

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Rendition of two cancerous tumor cells on healthy tissue © NikahGeh - stock.adobe.com

Researchers at the Chinese Academy of Sciences have developed an optical detection strategy for circulating tumor cells (CTCs), combining machine learning (ML) and dual-modal surface-enhanced Raman spectroscopy (SERS). This approach offers high sensitivity, specificity, and efficiency, potentially advancing early cancer diagnosis.

Liquid pharmaceutical  production line © KamokamoZa - stock.adobe.com

Researchers from the University of Liege have demonstrated the potential of surface-enhanced transmission Raman spectroscopy (SETRS) for detecting impurities in pharmaceuticals. The study highlights SETRS’s superior sensitivity, precision, and efficiency in quantifying toxic impurities like 4-aminophenol (4-AP), offering a promising alternative to traditional methods.

Researchers have developed a new substrate for surface-enhanced Raman spectroscopy (SERS) using two-dimensional amorphous titanium dioxide/silver (a-TiO2/Ag) nanosheets. This innovation promises significantly higher sensitivity and better uniformity in detecting various substances, potentially transforming applications in analytical spectroscopy and materials science.