Application Notes: Mass Spectrometry

This work will demonstrate a simple methodology using automated solid-phase extraction (SPE) and HPLC coupled with mass spectrometric detection. This work will demonstrate a simple methodology using automated solid-phase extraction (SPE) and HPLC coupled with mass spectrometric detection. This work will demonstrate a simple methodology using automated solid-phase extraction (SPE) and HPLC coupled with mass spectrometric detection.

Detecting impurities in any chemical reaction is becoming increasingly important to detect those present at low levels (for example, 0.5%).

The sensitive, selective, and real-time analysis characteristic of the SIFT-MS technique provides simple, robust, and continuous analysis of extremely diverse odor compounds at trace levels in air. This application note illustrates instantaneous, broad spectrum odor analysis with monitoring data from a chicken meat production facility.

A rapid, accurate, and reproducible method was developed for high-throughput testing of nicotine, cotinine, trans-3’-hydroxycotinine, nornicotine, norcotinine, and anabasine in urine. Data show that a fast and highly efficient analysis of these basic compounds can be achieved with the Raptor Biphenyl column using standard reversed-phase LC–MS mobile phases that are compatible with a variety of LC–MS instrumentation.

Bruker Daltonics, Inc.

A much discussed issue related to near infrared analysis (NIR) is the necessity of sample preparation. Ground and unground samples of wheat were analyzed to determine how truly necessary it is to homogenize samples before NIR analysis. The new Retsch TWISTER mill, specifically designed for NIR sample preparation, was utilized for this comparative study.

Increasing temperature can cause chemical changes, alter reaction rates, concentrate an aqueous sample, or evaporate a solvent. These transformations can be readily monitored by diamond ATR spectroscopy. This note explores the use of a diamond ATR to examine heat-induced changes in the clay.

There are nearly one thousand pesticides used in modern agricultural practice, and the residues of pesticides in the food from plant origins have been an increasing concern for consumers worldwide. Monitoring programs based analytical methodologies are established to ensure that the pesticide levels in plant foods are in compliance with national and international laws. However, the diversity of pesticides and complexity of food sample matrix present ongoing challenges for analytical chemists to meet the increasingly stringent requirements for sensitivity, precision, and throughput.

There are currently more than 1000 pesticides in use worldwide in the production of foodstuffs. There is a significant risk to human health and the environment due to increased pesticide use, poor agricultural practices and illegal use.

Thermogravimetric analysis (TGA) measures the change in the weight of a sample as a function of temperature.

Applied Biosystems/MDS SCIEX

Thermo Fisher Scientific

Thermo Fisher Scientific

Hitachi High Technologies America, Inc.

Advanced Chemistry Development, Inc.(ACD/Labs)

Applied Instrument Technologies

Hitachi High Technologies America, Inc.

BURLE Electro-Optics, Inc.

Gabriela Zurek, Birgit Schneider, and Carsten Baessmann, Bruker Daltonik GmbH

Michael Leist, ray Leiser, and Andrew Toms, Varian, Inc.