Application Notes: Mass Spectrometry

Synthetic copies of endogenous steroids are chemically and pharmacologically identical to their endogenous analogs. Analyzing isotopes of the steroids provide characteristic isotope fingerprints of urinary steroids and offer a discrimination framework.

Analysis of cocaine seized from an “aircraft drop” in Uruguay led to the discovery of a previously unknown coca growing region in northern Bolivia.

This work demonstrates a high throughput method for drinking water testing following EPA 200.8 leveraging PerkinElmer's NexION® HTS sample introduction module, delivering 3-5 times faster sample-to-sample analysis.

This application note describes a method for the ultra-low detection and characterization of hexavalent chromium in potable waters, in less than eight minutes, leveraging PerkinElmer's NexSARTM HPLC-ICP-MS speciation solution.

This work shows a method for the measurement of hexavalent chromium in different toy material categories in accordance with method EN 71-3 Category II, leveraging PerkinElmer's NexSARTM HPLC-ICP-MS speciation solution.

This study presents a reversed-phase ion-pairing method for the complete separation and accurate quantification of the main arsenic species in commercially available apple juices in under three minutes, using PerkinElmer's NexSARTM HPLC-ICP-MS speciation solution.

This application note discusses the hyphenation of a new in-line particle counter (PerkinElmer LPC 500TM) to an ICP-OES (PerkinElmer Avio® 500) for combined particle counting and wear metals analysis of in-service oils in a single run.

This study describes the analysis of lithium metaborate fusion samples using PerkinElmer's Avio® 500 ICP-OES, with a focus on long-term stability, leveraging the benefits of instrumental design characteristics when analyzing high-TDS samples.

This application note provides insights for the transition of optical nanostructures from design to volume NIL manufacturing using wire grid polarizer as an example.

This application note demonstrates analysis of elemental impurities, such as arsenic, in vitamin B12 according to USP chapter , using triple quadrupole ICP-MS.

This application note demonstrates how the PlasmaQuant MS provides low detection limits, accurate results and long-term stability analyzing volatile solvents.

Mercury is a persistent pollutant often exacerbated by human activities. A historical but pertinent case of effects of industrial pollution on the human population in Minimata, Japan is reviewed.

This application note demonstrates the routine automated multi-element analysis of environmental samples using triple quadrupole ICP-MS.

Chemically characterize lithium-ion batteries with Renishaw’s inVia Raman microscope.

Standardized methods (or official international methods) exist for stable isotope analysis of food and beverage samples and are aimed at protecting product origin, authenticity and label claims.

* Achieving high sensitivity and selectivity in complex matrices. * Useful tools and tips for ICP-QQQ * Environmental applications for ICP-MS

Single Reaction Chamber (SRC) microwave digestion allows for simultaneous digestion of up to 15 different sample types at temperatures as high as 300°C, greatly streamlining the sample preparation process.

Spectral Systems has developed its Diamond XP-BBAR™ coating with spectral performance. The SNR is about 30% better through most of the analysis region of a typical FT-IR instrument.

This application note details a GC-MS-based analytical method for the qualitative and quantitative determination of Irganox 1076 and 1010 in polyethylene.

The Diablo 5000A RTGA-MS allows the process stream to be seen in real-time and provides quantitative data with reliable mass information. The result is visualization.

This work will demonstrate a simple methodology using automated solid-phase extraction (SPE) and HPLC coupled with mass spectrometric detection. This work will demonstrate a simple methodology using automated solid-phase extraction (SPE) and HPLC coupled with mass spectrometric detection. This work will demonstrate a simple methodology using automated solid-phase extraction (SPE) and HPLC coupled with mass spectrometric detection.

Detecting impurities in any chemical reaction is becoming increasingly important to detect those present at low levels (for example, 0.5%).

The sensitive, selective, and real-time analysis characteristic of the SIFT-MS technique provides simple, robust, and continuous analysis of extremely diverse odor compounds at trace levels in air. This application note illustrates instantaneous, broad spectrum odor analysis with monitoring data from a chicken meat production facility.

A rapid, accurate, and reproducible method was developed for high-throughput testing of nicotine, cotinine, trans-3’-hydroxycotinine, nornicotine, norcotinine, and anabasine in urine. Data show that a fast and highly efficient analysis of these basic compounds can be achieved with the Raptor Biphenyl column using standard reversed-phase LC–MS mobile phases that are compatible with a variety of LC–MS instrumentation.

Bruker Daltonics, Inc.

A much discussed issue related to near infrared analysis (NIR) is the necessity of sample preparation. Ground and unground samples of wheat were analyzed to determine how truly necessary it is to homogenize samples before NIR analysis. The new Retsch TWISTER mill, specifically designed for NIR sample preparation, was utilized for this comparative study.

Increasing temperature can cause chemical changes, alter reaction rates, concentrate an aqueous sample, or evaporate a solvent. These transformations can be readily monitored by diamond ATR spectroscopy. This note explores the use of a diamond ATR to examine heat-induced changes in the clay.

There are nearly one thousand pesticides used in modern agricultural practice, and the residues of pesticides in the food from plant origins have been an increasing concern for consumers worldwide. Monitoring programs based analytical methodologies are established to ensure that the pesticide levels in plant foods are in compliance with national and international laws. However, the diversity of pesticides and complexity of food sample matrix present ongoing challenges for analytical chemists to meet the increasingly stringent requirements for sensitivity, precision, and throughput.

There are currently more than 1000 pesticides in use worldwide in the production of foodstuffs. There is a significant risk to human health and the environment due to increased pesticide use, poor agricultural practices and illegal use.

The amaZon series is the next step in Bruker Daltonics' family of ion trap mass spectrometers.