Application Notes

Raman-based polymer process monitoring enables rapid optimization of polymerization conditions, improves process efficiency, and ensures optimal final form.

• Achieving low detection limits by minimizing contamination in sample prep • Economic approach to reducing reagent blanks in ICP-OES and ICP-MS • Automated acid reflux cleaning system for maximum efficiency

• How to balance compliance needs with creating useful SOPs. • Tips and tricks for ensuring consistency. • Why and how you should test your SOPs

As synthetic opioid overdose deaths continues to rise, the use of fentanyl and its analogues in legacy drugs are posing significant danger to communities and first responders. This application note describes the use of the Rigaku ResQ CQL 1064nm handheld Raman analyzer to provide both bulk and trace analysis of fentanyl and other narcotics.

Reliable TOC analysis using the NPOC method with TIC control, high throughput by parallel purge and analysis, comparing catalytic combustion with UV-chemical oxidation.

This note looks at incidences of polymorphism in drug development including advantages and challenges.

This study shows Raman imaging, atomic force microscopy and scanning near-field optical microscopy characterizing and depth-profiling polymer blends and layers.

This industry report describes how the DMA-80 evo provides fast and accurate results for the analysis of mercury in nutraceutical samples without any sample prep.

This industry report describes how the DMA-80 evo can analyze as soils, sludges, and wastewater under EPA method 7473 without any wet chemistry sample prep in only 5 min.

This report shows how direct mercury analysis is used in the cement industry for testing raw materials prior to kiln combustion to control for Hg emissions.

Learn how Direct Mercury Analysis by thermal decomposition and amalgamation provides an accurate and easy to use technique that overcomes the limitations of ICP-MS.

This industry report describes how the DMA-80 evo can be used to determine mercury in coal samples in compliance with ASTM method 6722-01.

Mercury content in fish is an environmental and food safety concern. Learn how fish tissue analysis is performed with no sample prep using the DMA-80 evo.

This application note demonstrates the routine automated multi-element analysis of environmental samples using triple quadrupole ICP-MS.

• Raman spectroscopy of streamlining pharma QC and formulation development • Implementing transmission Raman for fast content uniformity testing • Through-container identity verification of polysorbates 20, 40, 60, and 80

• Even with a relatively light sample load of 250 samples per week, remeasuring 15% of them adds up to 2 weeks per year. • That’s 2 weeks you could be using for something more value-adding (and less boring).

This industry report describes how the Milestone ultraWAVE can process large, dissimilar and difficult pharmaceutical samples quickly and easily – all without batching.

Analysis of fertilizer products gives the ratio of macronutrients, which must be correct to ensure optimal efficacy. Learn how the ETHOS UP can process highly reactive fertilizer samples, even in large sample amounts.

Many polymers are very stable and require high temperatures and pressures to completely digest. Learn how the ultraWAVE can process these samples quickly and easily, yielding superior analytical data.

This industry report describes how the ETHOS UP can process highly reactive food samples, even in large amounts, yielding superior digestion quality and analytical data.

This article compares the differences and advantages of Single Reaction Chamber (SRC) Technology to traditional rotor-based microwave systems and explains what to consider when selecting the optimal technology for your lab.

This industry report describes how a variety of samples from the cannabis industry were digested simultaneously using disposable vials with full analyte recovery.

Demand for trace metals analysis in environmental labs is growing due to stricter regulations, and the need for lower levels of detection increasing. Learn how the ETHOS UP is fully compatible with US EPA environmental methods with accurate and full control of the digestion process.

Celldex utilized MMS to successfully observe the HOS of monoclonal antibody samples in complex buffer systems including excipients such as amino acids and sugars.

BSA samples analyzed at different concentrations to study heat induced thermal denaturation. Results show excellent reproducibility between sample replicates, concentrations.

Novel IR technique, microfluidic modulation spectroscopy, to address the requirements of development laboratories for high-quality higher-order structure assessment