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Jennifer C. Hitchcock

Articles

Rapid Analysis of Selected Benzodiazepines by Automated SPE–MS-MS

May 01, 2015

A new method was developed and validated using automated on-line solid-phase extraction (SPE) with tandem mass spectrometry (MS). Urine samples were enzyme-hydrolyzed and diluted before detection. The validated method was applied to positive authentic urine samples to evaluate concordance with high performance liquid chromatography (HPLC)–MS-MS results.

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