The Application Notebook 02-01-2022

Semi-batch reactions offer several advantages over traditional batch reactions, such as greater selectivity of products, gradual addition of reactants for better process control, and the ability to isolate product as it is formed.

In this application note, we study a nicotine patch to reveal the active pharmaceutical ingredient (API) as well as the polymer layers encapsulating it via confocal Raman microscopy.

Sample digestion with the Milestone ultraWAVE takes around one hour including cool-down time.

This application note describes a correlative Raman–scanning electron microscope (SEM) investigation of a lithium-ion battery cathode before and after hundreds of charge cycles. The technique provides an exceptionally detailed chemical and structural analysis of degradation processes on the nanoscale.

Using an automated FT-IR reflection sampling accessory, the surface of a polymer-coated aluminum film was analyzed. Spectral results were used to investigate chemical uniformity across the sample area.

This application note demonstrates using ATR to examine the changes in surface orientation as a function of the distance from the injection point or gate.