	This article demonstrates the utility of portable Raman spectroscopy as a simple and versatile tool for in-situ monitoring of reactions using univariate analysis techniques such as peak trending, as well as multivariate analysis approaches to predict the end point of chemical reactions.

Applications of Portable Raman Spectroscopy E-Book

Articles in this Issue

The Versatility of Portable Raman in Process Development


	We investigated the feasibility of identifying different types of bacterial growth medium using a handheld Raman instrument with a proprietary baseline correction algorithm. Our data suggest that this instrument is capable of differentiating multiple types of growth medium and readily detects the change in the Raman signal when bacteria are present in the growth medium. These findings support the notion that a handheld Raman spectrometer may be used to distinguish highly-fluorescent biological samples without the use of surface-enhanced Raman scattering.

Discrimination of Bacterial Growth Media Using Portable Raman Spectroscopy with Background Fluorescence Subtraction


	Here, we report our pilot efforts to perform rapid screening of anti-infective drugs for confirmation of drug product quality using near-infrared (NIR) and Raman library methods. The methods reported are nondestructive toward the sample and are designed to facilitate rapid physical testing of drugs at the point of use or in a field setting.

Library-Based Screening of Pharmaceutical Materials by Handheld Raman and Near-Infrared Spectrometers

	Quality control in the food industry is a key issue that requires rapid, efficient, and selective methods that could discriminate the products, detect fraudulent or accidental adulterations, and identify the content of some biomarkers within a particular process of storage conditions. Along these lines, Raman spectroscopy in conjunction with the optical properties of metallic nanostructures is a powerful technique that can be implemented in food analysis.

Spectroscopy eBooks-03-01-2017