July 2nd 2025
A recent study presented a dual-method approach combining confocal micro-Raman spectroscopy and Nile Red-assisted fluorescence microscopy to enhance the accuracy and throughput of microplastics detection in environmental samples.
Study Explores Interaction Between 2-Phenylquinoline-polyamine Conjugate and Bovine Serum Albumin
August 21st 2023Researchers used a multi-faceted approach that combined UV-visible, fluorescence, and circular dichronism spectroscopy to study the interaction between a newly synthesized 2-phenylquinoline-polyamine conjugate (QPC) and bovine serum albumin (BSA).
Fluorescence Microscopy: A Conversation with Joseph Black Award Winner Mathew Horrocks
July 20th 2023Mathew Horrocks, the 2023 recipient of The Joseph Black Prize, shares his thoughts about his current work developing and using single-molecule and super-resolution microscopy techniques to study amyloid oligomers and their commonality regarding a variety of neurodegenerative disorders.
New Fluorescent Probe Developed for Detecting Aluminum (Al3+) Ions
May 12th 2023A new fluorescent probe designed and synthesized by researchers can effectively and selectively detect Al3+ ions through the coexistence of photo-induced electron transfer (PET) and twisted intramolecular charge transfer (TICT) mechanisms.
Key Steps to Follow in a FRET Experiment
August 1st 2022Förster resonance energy transfer (FRET) is a versatile part of the toolbox of fluorescence methods. This through-space, photon-less energy transfer process between a donor fluorophore and an acceptor chromophore is perhaps most famous for its utility as a “molecular ruler” that can resolve nanometer-scale distances. FRET is also a popular and advantageous basis for biomolecular assays and sensors.
Challenges of Spectrofluorometry, Part 1: Collect Data Right the First Time
October 1st 2021Analysts using fluorescence emission and fluorescence excitation spectroscopy may encounter several common problems in their measurements. This tutorial, the first of a three-part series, provides a procedure to help avoid them.