November 21st 2024
This update is designed to help researchers investigate samples at cryogenic temperatures.
Combining Spectroscopy with Microscopy for Advancing the Analysis of Forensically Relevant Traces
July 1st 2020Forensic traces are physical remnants of past events that provide critical information for criminal and civil investigations and adjudications. The scientific examination of traces is an incredibly valuable tool for forensic investigations, because the skilled interpretation of traces yields factual answers to a range of pertinent questions.
Total Reflection X-Ray Fluorescence Spectrometry for Metals and Nanoparticle Analysis
June 8th 2016Total reflection x-ray fluorescence (TXRF) spectrometry is an energy-dispersive x-ray technique that is used for elemental and chemical analysis, and is especially suitable for small-sample analyses. Ursula Fittschen, an assistant professor at Washington State University, is working on elemental microscopy and micro analysis. She has been using TXRF to analyze stainless steel metal release, and also airborne silver nanoparticles (NPs) from fabrics. Here, she describes the advantages and challenges of this technique.
Harmful Algal Bloom Species and Identification Strategies
November 12th 2015Application of simultaneous absorbance and fluorescence excitation-emission matrix (EEM) analysis to identify and classify freshwater planktonic algal species. Main foci were two major potentially toxic cyanobacterial species associated with algal bloom events in the Great Lakes.
High Throughput Chemical Screening with the LabSpec 6 MultiWell Module
May 14th 2015LabSpec 6 MultiWell module and HORIBA Raman systems enable non-destructive analysis with high throughput screening using arrayed sampling devices, automated sample movement, autofocus devices, and automated data acquisition to acquire spectra from hundreds of samples sequentially.
Dye-Protein Binding Monitored in a Microliter Volume Using Time-Resolved Fluorescence
May 14th 2015Time‐resolved Fluorescence can analyze potential health benefits from antioxidant activity of curcumin, found in turmeric. Curcuminoids, weakly fluorescent in aqueous solution, show quantum yield increases upon interaction with a protein, such as human serum albumin.
Medical Imaging with Filters and Quantum Dots
February 11th 2011The onset of nanotechnology and targeted therapy methods for a number of pathologies has made it increasingly more difficult to image effectively in the medical field. With that being said, the inception of quantum dots and the improvements to optical filters has made this once daunting task a common practice.
More Raman Analyses Less Fluorescence Interference
February 11th 2011In recent years, the spectroscopy community has observed rapid development of Raman instrumentation and its usefulness in a variety of applications. Routine Raman analysis with 785 nm excitation has served well for the great majority of industrial applications and has become the most favored instrument configuration.
Total Reflectance X-Ray Fluorescence Spectroscopy
February 11th 2011X-ray fluorescence spectroscopy (XRF) provides sensitive analysis of the atomic composition of samples. The technique is particularly well-suited for analyzing the elemental range from sodium to uranium, which covers the majority of the metallic elements.
Market Profile: Lifetime Fluorescence
March 1st 2009Lifetime fluorescence is a subset of fluorescence spectroscopy in which the time between excitation and relaxation is measured, rather than just the intensity of the emitted energy. The technique is used primarily in biological applications, but has a number of other uses as well. Lifetime fluorescence is a well-established niche market.
Technology Forum: Fluorescence
November 5th 2008This month's Technology Forum looks at the topic of fluorescence and the trends and issues surrounding it. Joining us for this discussion are David M. Jameson, Ph.D., University of Hawaii at Manoa; Michael W. Allen, Ph.D, Product Manager, Thermo Fisher Scientific; and Patrick J. Treado, Founder & CTO, ChemImage Corporation.