Imaging

Our annual review of new products for atomic and molecular spectroscopy, including details by category and highlights of overarching trends.

Salvatore La Cavera III and his colleagues in the Faculty of Engineering at the University of Nottingham, in Nottingham, United Kingdom have developed a novel measurement system consisting of two ultrafast lasers that excite and detect high-frequency ultrasound from a nano-transducer fabricated onto the tip of a single-mode optical fiber.

Professor Rohit Bhargava and his team at the University of Illinois, where they have established the Cancer Center at Illinois, are advancing research in tumor microenvironments, using techniques such as high-definition Fourier transform infrared (HD-FT-IR) coupled with machine learning. We recently spoke to Bhargava about this work.

This article discusses coherent Raman imaging and how it can visualize and quantify cutaneous pharmacokinetics (PK).

Inline FT-NIR and offline terahertz Raman imaging analysis are used to characterize active pharmaceutical ingredient (API) crystallinity and to monitor different solid physical states of the API, to control process parameters of hot melt extrusion.

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Recent technical advances in biomedical Raman imaging pave a way to its application in the biomedical fields, where morphological information of samples provides rich information. A recent technical conference in Osaka, Japan, explored these developments.

An SPR experiment is composed of several steps, from ligands immobilization to data analysis. Results can be reached using a SPRi system for real time and label-free, specific and sensitive interactions.

Surface Plasmon Resonance imaging (SPRi) instruments enable a large number of different label-free molecular interactions to be monitored simultaneously and in parallel in a single experiment. This multiplexing capability will be demonstrated using an antibody SPRi-Biochip™.

Taking advantage of the multiplexing capabilities of SPR imaging, combined with the flexibility of the SPRi-Arrayer can help speed up the optimization steps necessary prior to kinetics analysis.

Here, hyperspectral imaging was used to simultaneously estimate chlorophyll and water content of Gannan navel orange leaves.

Scientists from IBM Research used an atomic force microscope to create the first-ever close-up image of a single molecule.

The authors look at the ways in which an imaging FT-IR microscope system with an integrated linear array detector can aid in the examination of a wide array of samples.

The author discusses the use of filters in optical microscopy and the advantages that have been gained as a result of developments in filter technology.

The author discusses the improvements offered by silicon drift detector energy dispersive X-ray spectrometry (SDD-EDS) systems over the classic Si(Li)-EDS for mapping the compositional microstructure of matter with scanning electron microscopy (SEM).

In this article, the authors discuss the need for protection against chemical attacks and the role of passive imaging spectroradiometers in the detection of remote chemical agents.

The author discusses how researchers can gain the most accurate and useful data from their equipment by employing careful sampling and microscope techniques and following a few common best practices.