Molecular Spectroscopy

What does the rise of portable and handheld spectroscopic instrumentation tell us?

A recent study used a multi-technique analytical approach to characterize the 2021 Tiglit meteorite, revealing unexpected mineral phases that point to a more complex history of shock events and post-fall alteration.

Metrohm's new i-Raman Platform is designed for both researchers and industry professionals alike. This Q&A overview provides the necessary information users would want to know.

In this overview, we explore how spectroscopy is advancing the agriculture industry.

A continuation of our recap of a recent study published in Microchemical Journal highlights the implications of how Raman spectroscopy can help analyze ancient DNA remains.

A recent study shows that non-destructive Raman spectroscopy measurements of protein-to-mineral ratios in ancient teeth can accurately predict endogenous DNA preservation, enabling archaeologists to pre-screen specimens and avoid unnecessary destructive sampling.

In this tutorial, we break down these vibrational spectroscopy advancements and what we can expect in the months and years ahead.

The final FDA guidance on Computer Software Assurance (CSA) was released in September 2025. This was followed by an update in Feb 2026 incorporating Quality Management System (QMS) based on ISO 13485:2016. Many proponents particularly outside of the medical device ecosystem have said that CSA will replace Computerised System Validation (CSV). But will it? Really?

This column will show Raman results and ATEEM fluorescence whose correlations indicate that important information is available non-destructively.

A study published in the Journal of Raman Spectroscopy reports the detection of polyethylene, PET, and nylon microplastics in Greece’s remote Dragon Lake on Mt. Tymfi.

In this "Molecular Spectroscopy Workbench" column, a new spectroscopy, called A-TEEM, is explored.

Researchers at Beijing University of Chemical Technology have developed a rapid online Raman spectroscopy method that accelerates real-time detection and strain screening of the bio-aviation fuel precursor β-farnesene.

This review article highlights how a new review by Da-Wen Sun demonstrates that integrating spectroscopy with chemometric techniques can significantly improve cold chain food quality monitoring, authentication, and overall system efficiency.

A recent study investigated how structural phase changes inside sensing materials dynamically influence performance during gas exposure.

The study reveals that infrared and Raman spectroscopy can accurately identify dye sources and detect light-induced chemical degradation in culturally significant Māori harakeke fibers.

A new study led by Meirong Liu at the Beijing National Laboratory for Molecular Sciences provides a comprehensive framework to eliminate instrumental and experimental artifacts in photoluminescence spectroscopy.

A recently developed sensor demonstrated that it could improve tannic acid detection in both food and environmental systems.

Geraldine L. Richmond, Presidential Chair in Science at the University of Oregon, has been awarded the 2025 NYSAS Gold Medal for her pioneering research on molecular interactions at liquid interfaces.

In the second part of a three-part interview, Lingyan Shi recaps the award technical session that she chaired at the SciX Conference, highlighting the speakers she invited and what they discussed.

As part of our coverage of the SciX Conference, Spectroscopy sat down with Witte, a graduate student at The Ohio State University, to talk about how machine learning (ML) algorithms can differentiate between spectral features associated with radiation dose and those reflecting temporal changes post-exposure, as well as the benefits of using Raman spectroscopy to detect and quantify radiation-induced molecular changes.

Researchers utilize Raman spectroscopy to uncover the lost colors of prehistoric mollusk shells, revealing their cultural significance and aesthetic choices.

Recently, a team of researchers from Chongqing University (China) developed a new Raman spectroscopy technique that could significantly improve natural gas monitoring and leak detection systems.

In Part 2 of this “Inside the Laboratory,” feature on George Shields, a professor of chemistry at Furman University and the founder and director of the Molecular Education and Research Consortium in Undergraduate Computational ChemistRY (MERCURY), Consortium, we discuss his research into computational approaches to improve our understanding of molecular behavior in both biochemistry and atmospheric chemistry and his work applying replica exchange molecular dynamics (REMD) for breast cancer drug design.

This Icons of Spectroscopy Series article features E. Bright Wilson, a pioneer of chemical physics. Wilson’s contributions to infrared, Raman, and microwave spectroscopy provided the theoretical and practical foundation for analyzing molecular structure and dynamics. As a revered professor at Harvard and coauthor of landmark texts, he mentored nearly 150 students and researchers, leaving a lasting legacy of scientific excellence and integrity.