Molecular Spectroscopy

Researchers use EC-SERS to reveal the first detailed structural study of hU-II peptide in aqueous solution, paving the way for new drug development.

Researchers at McGill University have developed a fast, eco-friendly method using portable Raman spectroscopy and deep learning to accurately assess the antioxidant content of maple syrup on-site.

Researchers at Guangdong University of Technology have developed a fast, non-destructive Raman spectroscopy method to accurately detect active ingredients in complex drug formulations.

A recent study published in the Journal of Archaeological Science: Reports reveals that a multi-headed snake motif at Argentina's La Candelaria rock shelter was created through multiple painting events over time.

The 78th International Symposium on Molecular Spectroscopy (ISMS) is set to take place this year from June 23rd to 27th, 2025. Here is what attendees can expect.

Researchers at Qiqihar Medical University have developed a dual-channel fluorescent probe, PYL-NBD, that enables highly sensitive, rapid, and selective detection of biothiols in food, pharmaceuticals, and living organisms.

A new study published in Spectrochimica Acta Part A by Dominik Heger and colleagues at Masaryk University reveals that phenol's photophysical properties change significantly when frozen, potentially enabling its breakdown by sunlight in icy environments.

A recent study demonstrated the utility of Raman spectroscopy and machine learning (ML) algorithms to classify plastic types found in waste of electric and electronic equipment (WEEE) streams.

A recent study by Southeast University researchers presented a cost-effective, high-accuracy solution for pharmaceutical quality control.

Researchers in China have developed a rapid, non-destructive Raman spectroscopy method that accurately detects active components in complex drug formulations by combining advanced algorithms to eliminate noise and fluorescence interference.

Tianjin University researchers develop an advanced AI model to enhance food safety.

A compilation of some of the top articles from our Molecular Spectroscopy Workbench column is presented.

In this Icons of Spectroscopy column, Executive Editor Jerome Workman Jr. delves into Part II of the Raman Effect, discovered by C. V. Raman, a physicist whose major contributions to vibrational spectroscopy have helped shape the field and advance one of the most important quantum-based spectroscopy tools of recent generations.

HORIBA has released three new products including tools for Raman screening, advanced molecular fingerprinting, and atomic fingerprinting. Two of these new tools will be highlighted during Pittcon.

In this column, I describe what I believe may be the origin of this fluorescence emission and support my conjecture with some measurements of polycyclic aromatic hydrocarbons (PAHs). Understanding the origin of these interfering backgrounds may enable you to design experiments with less interference, avoid the laser illuminations that make things worse, or both.

Last year, we released a content series titled “Advancing Agriculture for Future Generations.” Here, we compile some of the latest studies in this space.

A recent study out of China explored using a new continuous solid-phase extraction spectroscopy (CSPES) device to monitor water quality.

To improve the robustness and accuracy of logistic regression identification method, a new Raman spectroscopy identification method was proposed that combines a distributionally robust optimization technique and fused lasso technique with logistic regression. Then, Raman spectroscopy was used to analyze two types of dairy products that were collected for anti-jamming identification testing to verify the effectiveness of the new method.

A recent study from researchers in Brazil examined a-pinene’s chemical composition using mid-infrared (MIR) Fourier transform infrared (FT-IR) spectroscopy.

A recent study from Shanghai University demonstrated aa novel method for identifying and quantifying animal-origin milk powders.

A recent study demonstrates the successful development of in-line monitoring techniques using Raman spectroscopy and advanced modeling for titanium dioxide-free tablet coatings.

A recent study examined how Raman spectroscopy, when combined with machine learning (ML), can detect and analyze fertilizer nutrients.

A recent study looked at how spectroscopy can be used to differentiate ink based on its color and brand.

Researchers have developed a novel three-step hybrid variable selection strategy, SiPLS-RF(VIM)-IMIV, to enhance the accuracy and efficiency of soil potassium measurement using near-infrared spectroscopy, offering significant advancements for precision agriculture and real-time soil monitoring.

A recent study from China explored a new, non-destructive method combining terahertz time-domain spectroscopy (THz-TDS) and machine learning to accurately classify wheat gluten strength.

Because there is a different Raman signature for each of the polymorphs as well as the contaminants, Raman microscopy is an ideal tool for analyzing the structure of these materials as well as identifying possible contaminants that would also interfere with performance.

This year-in-review showcases the standout technical articles, compelling interviews, and key news stories that defined the pages of Spectroscopy. In this year in review, the editors of Spectroscopy highlight some of the top published technical articles, interviews, and news content published.

A recent study examined the role that Raman spectroscopy is playing in disease diagnosis.

A recent study reveals widespread and increasing microplastic contamination in the soils of Phoenix and the Sonoran Desert, highlighting significant environmental concerns and the need for further research into their sources and impacts.

Researchers from Northwest University in Xi’an, China, developed a novel portable Raman spectroscopy method with advanced chemometric techniques to accurately quantify harmful polycyclic aromatic hydrocarbons (PAHs) in oily sludge.