Molecular Spectroscopy

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Cancer research | Image Credit: © Catalin - stock.adobe.com
The Role of Raman Spectroscopy in Modern Cancer Research

July 15th 2025

A compilation of articles that explore the role of Raman spectroscopy in cancer research is presented.

Wooden spoons with sugar, sweetener on blue background. Generated with AI. | Image Credit: © Vadym - stock.adobe.com.
Rapid Sweetener Detection Achieved Through Raman Spectroscopy and Machine Learning

July 10th 2025

A glowing yellow and orange LED matrix creates a vibrant, illuminated digital grid pattern. Generated by AI. | Image Credit: © Jeannaa - stock.adobe.com
Lanthanum-Based Blue-Emitting Phosphor Shows Promise for Solid-State Lighting Applications

June 30th 2025

Light micrograph depicting a liver needle biopsy in haemochromatosis. This liver biopsy reveals hepatocytes with distinct brown iron deposits and highlights a fibrotic portal tract at the top. Generated with AI. | Image Credit: © Levan - stock.adobe.com
Highlighting the 2D-Photoacoustic Imaging Capabilities of Newly Developed PABDP1-4 Probes

June 23rd 2025

Prepared for frying, butchered various portions of raw chicken meat. Set of raw chicken fillet, thigh, wings, strips and legs on the background of the culinary table with spices and cherry tomatoes | Image Credit: © Mikhaylovskiy - stock.adobe.com
Fluorescence Emission and Raman Spectroscopy Offer Greater Insight into Poultry Meat Quality

June 19th 2025

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Recording the Raman Spectrum of a Single Molecule

Recording the Raman Spectrum of a Single Molecule

September 2nd 2021

Analytical chemists are continually striving to advance techniques to make it possible to observe and measure matter and processes at smaller and smaller scales. Professor Vartkess Ara Apkarian and his team at the University of California, Irvine have made a significant breakthrough in this quest: They have recorded the Raman spectrum of a single azobenzene thiol molecule. The approach, which breaks common tenets about surface-enhanced Raman scattering/spectroscopy (SERS) and tip-enhanced Raman spectroscopy (TERS), involved imaging an isolated azobenzene thiol molecule on an atomically flat gold surface, then picking it up and recording its Raman spectrum using an electrochemically etched silver tip, in an ultrahigh vacuum cryogenic scanning tunneling microscope. For the resulting paper detailing the effort [1], Apkarian and his associates are the 2021 recipients of the William F. Meggers Award, given annually by the Society for Applied Spectroscopy to the authors of the outstanding paper appearing in the journal Applied Spectroscopy. We spoke to Apkarian about this research, and what being awarded this honor means to him and his team. This interview is part of an ongoing series with the winners of awards that are presented at the annual SciX conference. The award will be presented to Apkarian at this fall’s event, which will be held in person in Providence, Rhode Island, September 28–October 1.