Molecular Spectroscopy

Particle-correlated Raman spectroscopy (PCRS) combines automated optical imaging and Raman analysis to link particle morphology with chemical identity, enabling high-throughput, reproducible characterization of diverse particulate samples, as demonstrated in pharmaceutical nasal spray analysis

Spectroscopy’s “What’s Nu” newsletter in May highlights the development of lasers in spectroscopy, compensating for repack variation in near-infrared (NIR) spectroscopy, and validity by design.

How is spectroscopy being used to detect methane and contribute to sustainability missions?

What were attendees talking about the most at Spring SciX?

Autofluorescence can obscure or overwhelm the Raman signal in biological samples. Do workaround solutions exist to combat this problem?

How has Raman spectroscopy been applied to the development of materials that are important in technology?

In this overview of the upcoming International Symposium for Molecular Spectroscopy (ISMS), we discuss the awards given out at the conference.

A systematic review from Beijing researchers maps how surface-enhanced and high-speed Raman technologies are reshaping what forensic examiners can extract from a single latent print.

The 79th meeting of the International Symposium on Molecular Spectroscopy is set to take place in June. Here’s what attendees should know.

Researchers combined two analytical techniques to characterize individual microplastic particles with both elemental and molecular detail.

A comprehensive review from the University of Porto identifies critical bottlenecks in biologics analysis and maps a technology-driven path forward.

What does the rise of portable and handheld spectroscopic instrumentation tell us?

A recent study used a multi-technique analytical approach to characterize the 2021 Tiglit meteorite, revealing unexpected mineral phases that point to a more complex history of shock events and post-fall alteration.

Metrohm's new i-Raman Platform is designed for both researchers and industry professionals alike. This Q&A overview provides the necessary information users would want to know.

In this overview, we explore how spectroscopy is advancing the agriculture industry.

A continuation of our recap of a recent study published in Microchemical Journal highlights the implications of how Raman spectroscopy can help analyze ancient DNA remains.

A recent study shows that non-destructive Raman spectroscopy measurements of protein-to-mineral ratios in ancient teeth can accurately predict endogenous DNA preservation, enabling archaeologists to pre-screen specimens and avoid unnecessary destructive sampling.

This brief tutorial offers an overview of Raman spectroscopy and the scientist responsible for discovering this technique.

A recent review article explores how machine learning (ML)-assisted Raman spectral classification is being used in applications such as biomedicine and material analysis.

In this tutorial, we break down these vibrational spectroscopy advancements and what we can expect in the months and years ahead.

The final FDA guidance on Computer Software Assurance (CSA) was released in September 2025. This was followed by an update in Feb 2026 incorporating Quality Management System (QMS) based on ISO 13485:2016. Many proponents particularly outside of the medical device ecosystem have said that CSA will replace Computerised System Validation (CSV). But will it? Really?

This column will show Raman results and ATEEM fluorescence whose correlations indicate that important information is available non-destructively.

In Part III of our conversation with David Clases, we discuss how optical trapping better enables polymer identification via Raman spectroscopy, and where ICP-MS research is heading in the future.

In this interview clip, David Clasas of the University of Graz discusses the trapping mechanism of the OF2i and how it improves downstream Raman and ICP-TOFMS measurements and also highlights the multimodal approach his team used to improve microplastic analysis.

A study published in the Journal of Raman Spectroscopy reports the detection of polyethylene, PET, and nylon microplastics in Greece’s remote Dragon Lake on Mt. Tymfi.