Molecular Spectroscopy

The field of analytical chemistry is well established. It’s time to develop the field of analytical biology—an emerging discipline that blends various research fields to provide a holistic view of biological phenomena.

Miri Park of the Fraunhofer Institute for Environmental, Safety, and Energy Technologies is examining how Raman spectroscopy could aid non-destructive sensing in agricultural science. Recently, Park sat down with Spectroscopy to discuss micro-Raman spectroscopy's role in assessing crop quality, particularly secondary metabolites, across different contexts (in vitro, in vivo, and in situ), while suggesting future research for broader application possibilities.

A recent study out of North-Eastern Hill University in India explores a new method that could aid the treatment of Alzheimer’s disease in patients.

A truly innovative approach to Raman spectral analysis is introduced in a newly published Applied Spectroscopy paper, utilizing a dynamic neural network modeling to significantly enhance baseline correction accuracy and offering a paradigm shift in spectral preprocessing.

The use of polarized Raman microscopy to complement the polarized light micrographs of spherulites in polymers reveals much about the orientation behavior of the lamellae in spherulites.

Researchers at NASA's Johnson Space Center, led by Ryan S. Jakubek, have unveiled a novel calibration method in Applied Spectroscopy that enhances the precision of Raman measurements conducted by the SHERLOC instrument on the Perseverance rover, providing a clearer and more accurate representation of intrinsic Raman spectral bandwidths on Mars.

An inside look at the fundamentals of Raman microscopy and how Raman can be utilized in chemical imaging and analysis, from its inception to modern applications.

This year’s conference included 12 tracks with sessions highlighting everything from mail security to art analysis and AI.

In a recent study, a team of researchers used Raman spectroscopy to study wood ash glass tessera from Malbork Madonna, revealing two phases detected in tessera for the first time, leucite and pseudowollastonite.

At the SciX Conference in Sparks, Nevada, Spectroscopy magazine sat down with Karen Esmonde-White of Endress+Hauser to talk about her career transition and how Raman spectroscopy has evolved over the years.

As a preview to SciX 2023, Spectroscopy magazine sat down with Juergen Popp of the Leibniz Institute of Photonic Technology to ask him about his research exploring the use of Raman spectroscopy in applications such as infectious diseases and cancer diagnostics.

A more successful blueprint for analyzing Raman spectral data is outlined by following the 11 important steps, which are outlined here.

In a recent study, a research team from China used Raman spectroscopy to uncover serum biomarkers for aplastic anemia and myelodysplastic syndromes.

Bruno Pagano, full Professor of Physical Chemistry at the University of Naples Federico II (Italy), and his team have turned to UV resonance Raman (UVRR) spectroscopy to better understand these interactions. Spectroscopy spoke to Prof. Pagano about his work and the potential of UVRR spectroscopy as a valuable tool for studying G-quadruplex structures in biologically relevant conditions.

In a recent study published in Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, two researchers from India studied the molecular composition of topiramate, revealing new insights.

A group of researchers from Beijing Technology and Business University developed a couple extraction algorithms and classification methods that could contribute toward ensuring the quality of wheat flour.

Dmitry Kurouski is this year’s recipient of the 2023 Emerging Leader in Molecular Spectroscopy Award for his work in using Raman spectroscopy for noninvasive, nondestructive analyses of biological materials.

Arzak Mohamed from Macquarie University in Australia broke down how she uses spectroscopy to analyze ancient manuscripts.

Scientists used spectroscopic techniques to learn more about paintings in the blue room of Ariadne’s house.

A recent study examined the interaction mechanism between methylene blue (NMB) and human serum albumin (HSA) and bovine serum albumin (BSA).

This year’s recipient of the Coblentz Award, Wei Xiong of the University of California, San Diego, is being honored for his work. Spectroscopy spoke to Xiong about his work and his feelings about receiving this award.

Shifted-excitation Raman difference spectroscopy (SERDS) is a technique that is capable of reducing the interference caused by fluorescence and improve the potential of Raman for distinguishing drug compounds in seized samples with fluorescent additives. Here, 43 drugs were analyzed to show the practical application of SERDS.

Author Jean-Pierre P. de Vera talks to Spectroscopy magazine about his study in which seven biomolecules were exposed to a simulated Martian environment outside the International Space Station (ISS) for a period of approximately 15 months.

The detection of life on other planets is a research area of focus for scientists in space exploration. In this Q&A, Andreas Riedo of the Physics Institute at the University of Bern offers his thoughts on how spectroscopy is being used to detect organic molecules that are relevant for life.

A Nature study reports the discovery of diverse organic-mineral associations in the Máaz and Séítah formations within Jezero crater on Mars, as observed by the Perseverance rover's SHERLOC instrument. The Raman and fluorescence findings indicate the presence of aromatic organic molecules within Martian soils.

The study of exoplanets, or planets outside of our solar system, is becoming increasingly important in space exploration. Scientists are working to characterize these planets and Raman spectroscopy is playing a key role. Andrew Mattioda, a research scientist at the National Aeronautics and Space Administration (NASA) Ames Research Center, is on the front lines of this research.

Researchers have developed a non-destructive method for identifying monoclonal antibody drug substances using Raman spectroscopy.

Researchers explore the antioxidant potential of Corema album (L.) D. Don by conducting a spectrochemical analysis on its leaf extracts. The study uncovers seasonal and sexual variations in antioxidant activity and phenolic compound composition, providing valuable insights for harnessing the bioactive properties of this plant species.

Researchers delve into the interaction between calf thymus DNA and an anticancer platinum (Pt) complex, uncovering its binding mechanism through spectroscopy and molecular dynamic simulations, offering valuable knowledge for future therapeutic advancements.

Researchers identify osmundacetone as a strong inhibitor of xanthine oxidase, revealing its interaction mechanism and paving the way for the development of novel uric acid-related disorder treatments.