Molecular Spectroscopy

A new study utilized genetic algorithms to optimize pre-processing strategies and classification models such as SVM, multilayer perceptron, and PLS-DA for improved lung cancer diagnosis using Raman spectra data.

Researchers have developed a rapid and accurate method combining front-face excitation-emission matrix fluorescence spectroscopy and interpretable deep learning to identify the storage year of Ningxia wolfberry, offering a green solution to combat fraudulent practices in the market.

An in situ high-temperature Raman scattering study of monoclinic m-Ag2Mo2O7 microrods reveals an irreversible first-order structural phase transition and melting process, according to new research.

Scientists have investigated the structural changes of a discotic liquid crystal during its phase transitions using a combination of quantum chemical approaches and vibrational spectroscopy.

Biomedical Raman imaging is growing in the biomedical space, where technical advances and new information processing tools and techniques aim to propel the field into the future. An upcoming conference in Atlanta, Georgia, will explore these developments while bringing scientists in this field together.

The article discusses a comparison of Raman imaging assessment methods for phase determination and stress analysis of zirconium oxide layers and their application in the development of zirconium alloys, especially for nuclear applications.

The study investigated the effects of symmetry relaxation on one- and two-photon absorption spectra of two bichromophore systems based on difluoroborate core linked by biphenylene or bianthracene moieties, and found that deviations from planarity of building blocks ensure maximum values of two-photon transition strengths.

Our annual review of new products for atomic and molecular spectroscopy, including details by category and highlights of overarching trends.

The DeepRaman method proposed in the study is an accurate, universal, and ready-to-use method for component identification in various application scenarios.

The researchers believe that the results of this study can contribute to the development of more effective and safer approaches to reduce the toxicity of heavy metals in food and the environment.

Dmitry Kurouski has won the 2023 Emerging Leader in Molecular Spectroscopy Award for his molecular spectroscopy studies revolving around plants.

Combining multiplex coherent anti-Stokes Raman scattering (MCARS) microscopy with automated data processing enables a simple and more accessible method for label-free bioimaging.

The significance of the smaller spectral region of the Raman spectrum, defined as the “fingerprint in the fingerprint” region, cannot be overstated when it comes to active pharmaceutical ingredient identity testing (API).

Studying the crystallinity of biodegradable polymers can be done without the complexity of larger instruments. Here’s how.

Handheld FT-Raman spectroscopy can complement GC–MS and IR in characterizing street drugs.

Extractables and leachable are typically studied using chromatographic techniques. This study explores what we can learn by using from using Raman microscopy for such studies.

Raman and XRF spectroscopy were used to examine paint in artwork, revealing the potential of both techniques to verify the authenticity of famous works of art.

Lu Wei of the California Institute of Technology, the 2022 winner of the Emerging Leader in Molecular Spectroscopy Award, is applying stimulated Raman scattering (SRS) microscopy for bioanalysis, spectroscopy-informed design of vibrational imaging probes, and sample-engineering strategies.

The relationship between the complexation amount of thorium (Th) and Suwannee River fulvic acid (SRFA) and the changes in Th concentration and pH were studied using differential spectroscopy and 3D excitation-emission matrix fluorescence spectroscopy (3D EEM).

This study shows that surface-enhanced Raman spectroscopy (SERS) of serum can provide an experimental basis for diagnosing leukemia in patients.

Here, we explain how Raman spectroscopy is valuable for characterizing industrially important carbon materials.

In this second part of this four-part series on spectroscopy instrument components, we take a closer look at optical components or subassemblies used for vibrational spectroscopy instruments.

Lu Wei, PhD, an assistant professor of chemistry at the California Institute of Technology, has won the 2022 Emerging Leader in Molecular Spectroscopy Award, which is presented by Spectroscopy magazine.

Our annual review of new products for atomic and molecular spectroscopy, including details by category and highlights of overarching trends.

The “fingerprint in the fingerprint” region is key for active pharmaceutical ingredient (API) identity testing. We explain why.

Raman spectra can help determine protein structure. Here’s how.

We explain how to characterize barium fluorohalides with Raman spectroscopy.

Innovative database search technology can help Raman spectroscopists identify molecular vibrations; here, we show how to use these tools more effectively.

In this study, the nitrophenol isomers, in solid and liquid phases, were analyzed using Raman spectroscopy, laying the groundwork for determining nitrophenol isomers in environmental monitoring with this technique.

Zac Schultz of The Ohio State University and his team used tip-enhanced Raman spectroscopy (TERS) and surface-enhanced Raman spectroscopy (SERS) with gold nanostars to investigate chemical reactions involved in protein–ligand binding. He recently spoke with Spectroscopy about his findings.