Application Notes: General

Learn practical aspects of analyzing microplastics with the Agilent 8700 LDIR and dealing with the difficulties of analyzing particles smaller than 20µm.

Learn how sub-micron resolution IR microscopy and high-speed spectroscopy overcomes the limitations of Raman spectroscopy for advanced failure analysis applications.

Learn how O-PTIR spectroscopy overcomes the limitations of Raman, providing automated measurement and chemID of sub-micron sized microplastics.

Learn how simultaneous O-PTIR and Raman provide high resolution IR imaging and spectroscopy of multilayer laminate film with minimal sample preparation.

Explains how O-PTIR spectroscopy overcomes the limitations of Raman spectroscopy by measuring defects in recessed semiconductor packaging structures.

Learn how sub-500nm resolution O-PTIR and co-located fluorescence microscopy combine to offer new insights and breakthroughs for life science research.

This application shows the depth profiling of mobile phone touch screens, facilitating visualization of the layered structure to illustrate technology advances.

Learn new ways to optimize molecular analysis with flexible, software-defined lock-in detection and stimulated Raman scattering (SRS) techniques. This powerful combination delivers unparalleled sensitivity, background-free imaging, and real-time insights so you can achieve more, faster.

The Geno/Grinder is a high-throughput plant and animal tissue homogenizer and cell lyser. It is equipped with an adjustable clamp that accommodates a full range of sample vials from 2 mL to 50 mL centrifuge tubes or up to six deep-well titer plates. It is specifically designed for rapid cell disruption, cell lysis and tissue homogenization through bead beating. This enables fast and efficient extraction of nucleic acids, proteins and other molecules. The Geno/Grinder incorporates a password-protected, touch screen control panel, enabling the user to program run time, rate, cycles and pause time.

Sample preparation is the process where a representative piece of material, chemical or substance is extracted from a larger amount, bulk or batch for subsequent analysis. Representative samples are selected to accurately reflect the larger group and represent the characteristics of the whole material. Ideally representative samples are homogeneous or similar in nature, but when that is not possible, the best attempts must be made to achieve samples which represent the majority of the characteristics of the larger grouping. The preparation of samples is one of the most important steps in analytical methods for many reasons, including the fact that some materials cannot be analyzed in an in-situ condition (such as proteins, DNA and RNA). Some samples have interfering substances and species that can produce faulty results. Sample preparation can include many processes, from reactions or treatment with chemical agents, to filtration, dilution, and extraction.

The Cryo-Blade is an ultra high-capacity cryogenic grinder for comminution and processing capability up to 1 kg. The homogeneity of the sample is very efficient. Only 1 g is needed as a representative test sample from a 1 kg ground batch. The high-throughput capability saves valuable time for your laboratory and meets Food and Drug Administration (FDA) regulations. The Cryo-Blade automatically dispenses liquid nitrogen to allow the sample to reach cryogenic temperatures and then activates a grinding phase to pulverize samples, resulting in repeatable and reproducible sample preparation. No liquid nitrogen handling required. When liquid nitrogen is not desired or available, the unit can be used with dry ice to achieve desired results.

Bead beating is an effective process used to disrupt a wide range of biological samples. It is achieved by rapidly agitating samples with grinding media (balls or beads) in a bead beater. Samples can be processed with or without buffer or solvent at room temperature or cryogenically. The Geno/Grinder® and MiniG® are high-throughput homogenizers that can process samples in deep well plates as well as other formats (up to 50 mL tubes). The homogenizers have a linear motion that focuses the kinetic energy of the grinding media on the sample instead of on the sides of the container. Consequently, even resilient samples such as seeds are most effectively homogenized by these linear motion bead beaters.

From entry-level items for the academia market to specialized instruments for the pharmaceutical, life sciences, chemical analysis, environmental testing, diagnostics and healthcare sectors, Cole-Parmer® offers high quality solutions for years of trouble-free operation.

Discover PerkinElmer's comprehensive and innovative solutions for the identification and quantification of microplastics.

This case study focuses on the University of Birmingham, where a UK-based research team is making great strides in microplastics analysis.

This application note reports the results of TG-GC/MS analysis of constituents of microplastics in suspended solids with the PerkinElmer Hyphenation System.

In this article, discover NIVA's studies and their experience working with the PerkinElmer Spectrum Two™ and Spotlight™ 400, FTIR Microscopy System for water research.

In this article, we talk to Dr. Jose Isagani Janairo, a Professor at De La Salle University, about his research into microplastics in marine commodities.

This application note describes the analysis of several different brands of bottled water using the PerkinElmer Spotlight 400 FT-IR Imaging system.

This work describes a method for the analysis of major and trace elements in plant-based food samples using the NexION® 2200 ICP-MS.

This Executive Summary presents a ‘total workflow’ approach to sample preparation for elemental analysis that helps labs identify opportunities for optimizing their operations in terms of productivity, quality, costs, and safety. Systems and tools are presented along with the benefits they provide to the sample prep workflow and, ultimately, to overall laboratory operations.

Learn of three real-life examples of Raman microscopy in battery research, focusing on lithium batteries to better understand the process both ex- and in-situ.

This work shows how the NexION® 1000 ICP-MS equipped with the All Matrix Solution (AMS) online gas dilution system is used to measure chloride content in materials.

This work demonstrates the ability of the Avio® 550 Max fully simultaneous ICP-OES to determine major and impurity components in black mass.

This work demonstrates the ability of the NexION® 2000 ICP-MS to accurately measure impurities in lithium salts commonly used in the production of lithium batteries.

This application note is a first step in the use of DES to extract critical metals from pure cathode materials used in LIBS using the Avio® 220 Max ICP-OES.

Learn how to simple and standard-compliant determine phosphorus in sewage sludge after microwave-assisted acid digestion.

This overview of advanced microparticle analysis shows how particles can be found, classified and then identified automatically using confocal Raman microscopy.