John Chasse

Spectroscopy spoke with Montes-Bayón of the University of Oviedo about her work with single cell ICP-MS to study the uptake and apoptotic status nanoplatinum treated cells.

This year’s recipient of the Coblentz Award, Wei Xiong of the University of California, San Diego, is being honored for his work. Spectroscopy spoke to Xiong about his work and his feelings about receiving this award.

In this interview, Peter Griffiths, 2023 recipient of the Ellis R. Lippincott Award, reflects over his storied career, as well as his most recent work, which focuses on measuring fine airborne particles within mining environments.

In this interview, James Chapman discusses his current and future research efforts, and how combining spectroscopy with machine learning tools can change how bacterial research is conducted.

Mathew Horrocks, the 2023 recipient of The Joseph Black Prize, shares his thoughts about his current work developing and using single-molecule and super-resolution microscopy techniques to study amyloid oligomers and their commonality regarding a variety of neurodegenerative disorders.

In this interview, Jürgen Popp discusses the importance of Raman spectroscopy, where it can make a difference, and how it can be evolved and improved on in the future.

Single-cell ICP-MS was used to study the uptake and apoptotic status of nanoplatinum (IV) treated cells, specifically selenized yeast, and the question of using commercialized reference material to validate single cell ICP-MS analysis is addressed.

This interview with Young Jong Lee highlights the work he and his team have done to reinvent solvent absorption compensation (SAC), and the potential it has across multiple forms of spectroscopy.

Gary McGeorge, Scientific Director at Bristol-Myers Squibb, spoke to us of the benefits and challenges associated with establishment of consistent resolutions while facilitating the steps associated with the implementation of process analytical technology (PAT).

ICP-MS was used to measure 46 different elements in 37 Azobé (Lophira alata) trees at two forest sites in Cameroon to determine the multi-elemental composition of trees in an effort to combat the illegal trade of timber.

Although milk is considered among the most complete and nutrition-rich natural foods, the concentration of vitamins and minerals in milk can vary depending on a variety of circumstances. Stelios Couris of the University of Patras and the Foundation for Research and Technology-Hellas (Patras, Greece) has been studying the inorganic elemental composition of a variety of milk samples using LIBS and spoke to Spectroscopy about this research.

Combining multiplex coherent anti-Stokes Raman scattering (MCARS) microscopy with automated data processing enables a simple and more accessible method for label-free bioimaging.

Glycoproteins are becoming popular in the pharmaceutical industry, prompting the need for an effective spectroscopic technique that can differentiate them. SERS is one such technique ideal for glycan analysis for several key reasons, which are discussed here.

Catherine Niu, a professor at the College of Engineering of the University of Saskatchewan in Canada and co-author of this paper, spoke to Spectroscopy about how she and her associates used X-ray photoelectron spectra and near-edge X-ray absorption fine structure (NEXAFS) spectroscopy analysis in their research.

Recently, at the 2022 SciX conference in Covington, Kentucky, Beatriz Fernandez, who is an Associate Professor at the University of Oviedo in Spain, presented, as part of the Technical Program, a discussion regarding the determination of proteins in single cells by ICP-MS using metal nanoclusters as labels of specific recognition reactions. Fernandez spoke to Spectroscopy about her presentation.

Harishchandra Singh, Graham King and associates have employed high energy synchrotron X-ray diffraction (HE-SXRD) experiments and an analytical model in order to predict the yield strength of cerium-modified super duplex stainless steel (SDSS) subjected to various cold- and cryo-deformation. Spectroscopy recently had the opportunity to discuss the experiments and the findings with Singh and King.

In the treatment of tuberculosis (TB), a contagious disease that causes 1.5 million deaths per year globally, early diagnosis is critical in order to control its spread. Unfortunately, standard tuberculosis diagnostic tests, such as sputum culture, can take days to weeks to yield results. In a recent paper, Ubaid Ullah of the Syed Babar Ali School of Science and Engineering in Pakistan and his colleagues demonstrate a quick, portable, easy-to-use, and non-invasive optical sensor based on sputum samples for tuberculosis detection using Raman spectroscopy to detect TB in a patient’s sputum supernatant. Ullah spoke to Spectroscopy about this sensor and its development.

Some macrofungal species are known for their ability to accumulate high concentrations of mercury in their fruit bodies. A recent paper by Simone Braeuer and colleagues of the University of Graz (Austria) and Ghent University (Belgium) discusses an efficient method developed for quantitative mapping of mercury and selenium in mushroom fruit bodies via laser ablation coupled to inductively coupled plasma–mass spectrometry with excellent limits of detection and high spatial resolution (down to 5 µm). Braeuer spoke to Spectroscopy about this paper.

Karen Faulds of the University of Strathclyde co-authored a paper where SESORS signals could be detected from nanotags at depths down to 48 mm for the first time using a handheld spatially offset Raman (SORS) instrument. She recently spoke to Spectroscopy about this and some of her other papers and the advances in the science that made them possible. Faulds is the 2022 recipient of the RSC Analytical Division Mid-Career Award. This interview is part of an ongoing series of interviews with the winners of awards that are presented at the annual SciX conference, which will be held this year from October 2 through October 7, in Covington, Kentucky.

Wei Min, of the Department of Chemistry at Columbia University in New York City, and his associates recently published a paper outlining their devising a set of multiplexed Raman molecular probes with sharp and mutually resolvable Raman peaks to simultaneously quantify cell surface proteins, endocytosis activities, and metabolic dynamics of an individual live cell. Min, who recently spoke to us about this work, is the 2022 recipient of the Craver Award, presented annually at FACSS SciX to recognize the efforts of young professional spectroscopists that have made significant contributions in applied analytical vibrational spectroscopy.

Igor Gornushkin and colleagues at BAM Federal Institute for Materials Research and Testing in Berlin, Germany studied the feasibility of using optical spectroscopy as a control method for laser metal deposition, and he recently spoke to us about this work. Gornushkin is the 2022 recipient of the Lester W. Strock Award from the New England Chapter of the Society for Applied Spectroscopy (SAS).

Noureddine Melikechi of the Department of Physics and Applied Physics at the University of Massachusetts (Lowell, MA) saw an urgent need for the development of an untargeted and unbiased method to distinguish Gulf War illness (GWI) patients from non-GWI patients; he and his associates utilized laser-induced breakdown spectroscopy (LIBS) in their efforts to meet that need.

Spray paint is often used by vandals for creating graffiti, as well as for criminals to leave signs, messages, and blots to conceal the left traces at the scene of their efforts. Rajinder Singh and his colleagues in the Department of Forensic Science at Punjabi University (Punjab, India) have used attenuated total reflectance Fourier transform infrared (ATR-FT-IR) spectroscopy for nondestructive analysis of 20 red spray paints of different manufacturers, which could possibly be encountered at a crime scene, particularly in case of vandalism. Singh spoke to Spectroscopy about the findings, and the paper that resulted from their efforts.

As global food supplies and security have been challenged by water scarcity and climate variations, the expected increase in food demand will require a corresponding increase in crop productivity and disruptive improvements in agricultural production systems, including implementing strategies to mitigate the degradation of crop yield caused by plant diseases. Several groups have explored the use of Raman spectroscopy for rapid diagnosis of such diseases.

A tutorial and spreadsheet for the validation and bottom-up uncertainty evaluation of quantifications performed by instrumental methods of analysis based on linear weighted calibrations were presented by Ricardo J.N. Bettencourt da Silva of the University of Lisbon in Lisbon, Portugal, and colleagues. This software tool was successfully applied to the determination of the mass concentration of Cd, Pb, As, Hg, Co, V, and Ni in a nasal spray by ICP-MS after samples dilution and acidification. Bettencourt da Silva spoke to Spectroscopy about applying this software tool and the implications for a better understanding of quantitative analytical results.

The limited availability of table-top extreme ultraviolet (XUV) sources with adequate fluxes and coherence properties has resulted in a lack of nonlinear XUV and X-ray spectroscopies to free-election lasers (FELs). Michael Zuerch of the Department of Chemistry at the University of California, Berkeley, along with colleagues from ten laboratories across three countries, has conducted the first extreme ultraviolet second harmonic generation (XUV-SHG) experiment above the Ti M edge (32.6 eV), also representing the first table-top demonstration of SHG at photon energies beyond the UV regime.

A tutorial and spreadsheet for the validation and uncertainty evaluation for ICP-MS analysis was successfully applied to determine multiple elements in a nasal spray.

Emmanuel Lalla of York University in Toronto, Ontario, Canada, as well as his co-authors, recently presented an in-depth characterization of a set of samples collected during a 28-day Mars analog mission conducted by the Austrian Space Forum in the Dhofar region of Oman. Lalla spoke to Spectroscopy about this research, as well as how various methods of spectroscopic analysis can complement each other in analysis.

Salvatore La Cavera III and his colleagues in the Faculty of Engineering at the University of Nottingham, in Nottingham, United Kingdom have developed a novel measurement system consisting of two ultrafast lasers that excite and detect high-frequency ultrasound from a nano-transducer fabricated onto the tip of a single-mode optical fiber.

Mark Meyerhoff has been exploring chemical sensors for biomedical applications. Because of his work, Meyerhoff has been awarded the 2021 ANACHEM award. Meyerhoff spoke to us about his work, his career, and what being presented this award at this fall’s SciX event means to him.