Spectroscopy-12-01-2015

Imaging techniques using vibrational spectroscopy, mass spectrometry (MS), and atomic force microscopy have all been advancing and gaining momentum in recent years. There is great potential power in these imaging techniques, particularly in the biomedical field. Thomas Bocklitz of at the Friedrich-Schiller-University Jena is working to better harness the power of these techniques by combining them.

The application of vibrational selection rules is usually taught with respect to the vibrational motions of individual molecules. However, many of the materials studied by infrared or Raman spectroscopy are solids and even single crystals. Furthermore, some materials such as covalent or ionic solids have no molecular species associated with them. Consequently, there is a need to understand the application of group theory for the determination of spectroscopically active vibrational modes of crystals. The correlation method is ideal for that purpose.

Some parts of the FDA’s new draft guidance for Development and Submission of NIR Analytical Procedures are reviewed and critiqued. What’s in it for spectroscopists?

Infrared spectroscopy is an appealing technique for application to forensic samples because it offers the benefits of being non-destructive and non-hazardous, fast, reasonably sensitive, and resistant to some of the interferences of many commonly used techniques. Our research team has been focusing on detecting biological fluids on fabrics, which are inherently anisotropic substrates for spectroscopy. The work presented here investigates the effect of azimuthal angle of the sample on the infrared diffuse reflection spectra of fabrics with a goal of removing sampling differences as a source of analytic variation.

The Rigaku RPF-SQX software automatically deconvolutes spectral peaks and models the sample matrix and X-ray absorption/enhancement effects using fundamental XRF equations. The RPF-SQX software is simple to use and offers many ways to craft a matrix model based on the specific fly ash composition, allowing semi-quantitative analysis without the use of reference standards.

Agilent Technologies Inc. (NYSE: A), a global leader in life sciences, diagnostics and applied chemical markets, is the premier laboratory partner for a better world. Agilent works with customers in more than 100 countries, providing instruments, software, services, and consumables for the entire laboratory workflow.

Our new and unique high tech manufactu-ring facility located in Quebec City, Canada, employs more than 220 people, including R&D, manufacturing, marketing, sales, and administrative groups. ABB is a leader in energy and automation technologies, allowing public services as well as industry, transport and infrastructure clients to improve their performance while reducing their impact on the environment. The ABB Group of companies operates in around 100 countries and employs about 140,000 people.

The largest Andor facility is based in Belfast, Northern Ireland, which is a new, purpose-built 50,000 sq. ft. premise. The premises include state of the art optical, electronic, and mechanical workshops, a 3000 sq. ft. class 1000 clean room, vacuum and electronic processing facilities. Andor also maintains sale and sales support facilities throughout the world close to our customers.

For all measurements, a Harrick Wire Grid Polarizer (KRS-5 substrate) was used. The polarizer was oriented in the same position for both background and sample measurements. All spectra were collected using an FT-IR spectrometer at an 8 cm-1 resolution averaged over 32 scans.

The 12 W miniature source has a higher voltage and a much higher emission current than our present miniature X-ray sources, which is an advantage for a number of applications.

Headquartered in Oslo, Norway, CAMO Software has global presence through our offices in the USA, Japan, India, and Australia.

These market- and technology-leading products are driving and facilitating many key application areas such as life science research, pharmaceutical analysis, applied analytical chemistry applications, materials research and nanotechnology, clinical research, molecular diagnostics, and homeland defense.

SuperGamut spectrographs and spectrometers, Nunavut CCD and InGaAs cameras, Mini-Lite Light Sources, Agility™ Raman Analyzers, RamSpec Raman Bench-top instruments, Nomadic and MovingLab Raman Microscopes, WaveCapture FBG Interrogators, IntelliGuard Optical Channel Performance Monitors, Portability Mass Spectrometer, and Hyperspectral Imaging.

lrradiance and LED measurements, gemology, chemometric analysis, thin-film measurement, color, fluorescence, laser induced breakdown spectroscopy, Raman spectroscopy, and process control.

EDAX headquarters is located in Mahwah, New Jersey, housing sales, engineering, technical support, and operations. EDAX is committed to providing the best possible support for our customers world-wide with sales, service, and applications support offices located in Japan, China, Singapore, The Netherlands, Germany, the United Kingdom, and the United States.

CEM's global headquarters, research laboratories, and manufacturing facilities are located in Matthews, North Carolina. The company has subsidiaries in the United Kingdom, Ireland, Germany, Italy, France, and Japan, as well as more than 50 distributors worldwide.

Edinburgh Instruments are part of the Techcomp Europe group, with all manufacturing facilities in Scotland. Sales, service, and applications facilities are located around the world.