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The Top 10 Most Influential Applications of Vibrational Spectroscopy in Environmental Analysis (2024-2026) ©  AthenStudio -chronicles-stock.adobe.com

Between 2024 and 2026, environmental applications of vibrational spectroscopy advanced rapidly through innovations in multimodal instrumentation (combining 2 or more distinct measurement techniques), spectral data fusion, portable sensing technologies, and the integration of chemometrics and machine learning (ML). Near-infrared (NIR), Fourier transform infrared (FTIR), and Raman spectroscopy were increasingly deployed to address pressing environmental challenges such as microplastics contamination, soil organic matter quantification, indoor air quality monitoring, and pesticide residue detection in food and ecological systems. This article reviews 10 influential peer-reviewed papers published during this period, providing expanded narrative discussions of their technical contributions and explaining why each paper represents a significant impact on the field.

From Latent Variables to Large Language Models: A Unified Glossary Bridging Chemometrics, Machine Learning, and Artificial Intelligence ©Leo Rohmann-chronicles-stock.adobe.com

Artificial intelligence and machine learning are rapidly reshaping how analytical data are modeled, interpreted, and deployed, but the conceptual foundation is already familiar to practitioners of chemometrics. Latent variables, calibration models, variance–bias tradeoffs, and multivariate optimization did not originate with neural networks; they have been central to spectroscopic data analysis for decades. This expanded glossary provides a rigorous, side-by-side translation between modern artificial intelligence (AI) terminology and established chemometric concepts. This glossary is intended to demystify AI terminology, while preserving statistical clarity. It is designed to help analytical scientists, spectroscopists, and chemometricians engage with modern data-driven methods without abandoning physical interpretability or statistical discipline.

In this blog post, Alexis Weber, a Field Applications Scientist at PerkinElmer, describes how early forensic-science ambitions inspired by NCIS and Bones evolved through education at University of Central Florida, University of New Haven, and University at Albany, SUNY into a PhD-level spectroscopy career and ultimately a dynamic Field Applications Scientist role at PerkinElmer, highlighting the value of exploring nontraditional science careers.

A study conducted at Lawrence Berkeley National Laboratory (Berkeley, California), with collaboration from the University of Michigan (Ann Arbor, Michigan), presented a comprehensive characterization of the gaseous UF6 LIBS plasma behavior, examining the effects of laser pulse width and wavelength on spectral characteristics and fundamental plasma properties through temporally resolved analysis, Boltzmann-plot temperature determination, and electron number density evaluation. Spectroscopy spoke to George Chan of the Lawrence Berkeley National Laboratory and corresponding author for the paper resulting from this work.

Artificial Intelligence as the Next Layer of Chemometrics ©  phonlamaiphoto -chronicles-stock.adobe.com

From a chemometric standpoint, artificial intelligence (AI) in spectroscopy is best understood as an extension of established multivariate methods rather than as a replacement. Most AI approaches closely parallel familiar tools such as regression, classification, and principal component analysis, but offer greater flexibility to handle nonlinear behavior, interacting physical and chemical effects, and large, heterogeneous datasets. By learning directly from raw spectra, AI methods can reduce reliance on manual preprocessing while still indicating which spectral regions influence predictions. In this sense, AI represents a developmental layer of chemometrics that enables classical concepts to operate effectively in modern spectroscopic systems. Overall, AI is best viewed as the next developmental layer of chemometrics, not as a competing discipline. As with all current AI programs, domain knowledge of analytical chemistry is essential for AI’s effective application. Knowing the boundaries of what is plausible in any chemical or modeling system allows fine-tuning of the models towards useful and reliable analytical results.