Application Notebook-02-02-2020

Application Notebook

Vol 35 No 2 Spectroscopy Feb 2020 Application Notebook PDF

February 02, 2020

Application Notebook February 2020

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Click the title above to open the Spectroscopy February 2020 special issue, Vol 35 No s2, in an interactive PDF format. Turn to page 65 for The Application Notebook.

A Robust, High Performance, Revolutionary Demountable ICP Torch

February 01, 2020

Atomic Spectroscopy

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Glass Expansion designed and patented the D-Torch, a revolutionary, demountable torch. The D-Torch uses high-precision engineering to provide the benefits of a demountable torch, such as lower running costs, chemical inertness, and configurable injector geometry, without compromising usability, performance, or durability. In this report, we discuss the effects of harsh matrices on torches, as well as the features, benefits, and improvements in analysis achieved with the D-Torch.

A Corrosive Liquid Investigated by Diamond ATR Infrared Spectroscopy

February 01, 2020

Molecular Spectroscopy

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Because of their corrosive properties, corrosive lipids are challenging to analyze by ATR-FT-IR. Repeated and prolonged analysis can damage many ATR crystals. Diamond ATR is a better choice for such applications than other ATR crystal materials like ZnSe and Ge. This application note examines a corrosive liquid as it becomes progressively more concentrated using diamond ATR.

Bioreactor Fermentation Monitoring with Raman Spectroscopy

February 01, 2020

Molecular Spectroscopy

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Raman spectroscopy’s high analytical selectivity and insensitivity to water is well suited for process monitoring in biotechnology. Here we explore the fermentation of glucose, a common feedstock, with a commonly used microorganism, yeast. Applying multivariate tools, we can monitor the main reactants and products with high sensitivity: glucose, ethanol, and carbon dioxide.

QTRam for Content Uniformity Analysis of Low-Dose Pharmaceutical Tablets

February 01, 2020

Molecular Spectroscopy

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Compressed tablet is the most common form of orally administered drug. The United States Pharmacopeia (USP) chapter requires that dosage uniformity of such products containing less than 25 mg or less than 25% active pharmaceutical ingredients (API) by weight must be analyzed for content uniformity, which is based on the assay of each API in a number of individual dosage units.

Tracking Photocuring via ATR-FT-IR with Illumination through the ATR Element

February 01, 2020

Molecular Spectroscopy

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The utility of the GladiATR diamond ATR, modified with an internal liquid light guide to illuminate the sample from underneath the ATR element, was explored to analyze the photo-polymerization of carbitol acrylate at 405 nm using 1 wt% TPO.

Gallium Nitride Quality and Stress Field Characterization with 3D Confocal Raman Imaging

February 01, 2020

Molecular Spectroscopy

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The quality and stress field properties of gallium nitride (GaN) crystals must be investigated in order to refine production processes. 3D Confocal Raman microscopy is uniquely capable of the chemical c and visualizing strain in this material.