Infrared (IR) Spectroscopy

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Man holding up a gold trophy cup | Image Credit: © Jag_cz - stock.adobe.com.

This year’s Emerging Leader in Molecular Spectroscopy Award recipient is Joseph P. Smith of Merck, whose research is significantly influencing pharmaceutical process development through his work in various spectroscopic techniques, biocatalysis, protein engineering, vaccine production, and advanced data analysis methods.

Depiction of Protein Molecules and Molecular Structures in Dynamic Biological Interactions ©  克 杜 - stock.adobe.com

Researchers at Nagoya University and RIKEN have developed a novel computational method to enhance the resolution of high-speed atomic force microscopy (HS-AFM) images for studying protein conformational transitions. The algorithm, normal mode flexible fitting-atomic force microscopy (NMFF-AFM), leverages normal-mode analysis to derive precise molecular models, potentially transforming the understanding of biomolecular dynamics.

3d illustration of water molecule © artegorov3@gmail - stock.adobe.com

Researchers from the Max Planck Institute for Polymer Research and the University of Cambridge have revealed new insights into the behavior of water molecules at the surface of saltwater using advanced vibrational sum-frequency generation spectroscopy (VSFG). Their findings challenge long-standing assumptions about ion distribution at these interfaces, which are critical in environmental and chemical processes.

A modern perovskite high performance solar cell ©  AA+W - stock.adobe.com

Researchers at King Saud University have successfully improved the efficiency of methylammonium lead triiodide (MAPbI3) perovskite solar cells by doping them with Germanium Sulfide (GeS). By enhancing the crystalline quality and surface morphology of the perovskite layer, the team achieved a power conversion efficiency (PCE) of 17.46%, making this doping technique a promising method for improving solar cell performance.

Dr. Rajinder Singh, Professor and former Head of the Department of Forensic Science, Punjabi University in Patiala, Punjab, India. Photo Credit: Rajinder Singh

As part of “The Future of Forensic Analysis” content series presented by Spectroscopy, we sat down with Dr. Rajinder Singh of Department of Forensic Science, Punjabi University, Patiala, to talk about his recent work using attenuated total reflectance Fourier transform infrared spectroscopy (ATR-FT-IR) to distinguish different animal species based on hair samples.

The Latest Spectroscopic Research in Agriculture Analysis ©  Dzikir - stock.adobe.com

Spectroscopic analytical techniques are crucial for the analysis of agricultural products. This review emphasizes the latest advancements in several key spectroscopic methods, including atomic, vibrational, molecular, electronic, and X-ray techniques. The applications of these analytical methods in detecting important quality parameters, adulteration, insects and rodent infestation, ripening, and other essential applications are discussed.

AI-Powered Spectroscopy in Rapid Food Analysis ©  Lila Patel - stock.adobe.com

A recent study reveals on the challenges and limitations of AI-driven spectroscopy methods for rapid food analysis. Despite the promise of these technologies, issues like small sample sizes, misuse of advanced modeling techniques, and validation problems hinder their effectiveness. The authors suggest guidelines for improving accuracy and reliability in both research and industrial settings.