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Sparks near Reno Nevada – Site of 2026 SciX Conference ©   DTM Media  -chronicles-stock.adobe.com

Wednesday's program at SciX 2026 kept returning to one question: can spectroscopy perform outside the controlled laboratory? Speakers took surface-enhanced Raman scattering (SERS), laser-induced breakdown spectroscopy (LIBS), mid-infrared photonics, chemometrics, and fluorescence excitation–emission matrix (EEM) spectroscopy into clinics, food plants, reactor coolant loops, brine fields, and drinking water supplies.

NIR Spectroscopy of the Brain and Other Complex Analyses, ©   Navaporn  -chronicles-stock.adobe.com

Near-infrared spectroscopy has quietly stopped being a niche calibration exercise and started acting like an autonomous diagnostic partner, reading consciousness in an injured brain, steering a fermenter without a human hand, and hunting invisible plastic in a glass of water. The tool chemists once used to check moisture in grain is now fusing with artificial intelligence to make decisions no spectrometer could make alone.

FACSS 2026 Award Interviews ©  Erin -chronicles-stock.adobe.com

Eight FACSS award winners at SciX 2026, One LIBS trailblazer. Forty-eight questions. And not one of them is a softball. Award season in spectroscopy usually means polite applause, a plaque, and a photo. We're not completely interested only in the award sessions. The eight scientists honored at SciX 2026 in Sparks, Nevada, along with LIBS researcher Alessandro De Giacomo, are pushing Raman into operating rooms, flying LIBS on drones, reading chemistry off Mars, and tracing toxic metals downwind of industrial sites. Their work makes big claims. In the coming days, Spectroscopy will sit down with eight of these researchers and ask whether those claims hold up. The interviews that follow won't just celebrate. They'll press on the gaps between simulation and experiment, between the lab bench and the clinic, and between a clever paper and an instrument someone will actually buy and use.

Spectral Frontiers: Past the Diffraction Limit (FT-IR Spectroscopy)

Fourier-transform infrared (FT-IR) spectroscopy, long the workhorse of molecular fingerprinting, is being reinvented by photothermal detection schemes and quantum cascade laser (QCL) sources that push spatial resolution and analysis speed far beyond classical dispersive and interferometric limits. New instrumentation such as optical photothermal infrared (O-PTIR) microscopy and laser direct infrared (LDIR) chemical imaging is enabling sub-micron, label-free chemical mapping of biological, environmental, and pharmaceutical samples. This article reviews the latest FT-IR-adjacent technologies, recent patents, and research driving the field, featuring perspectives from the scientists and instrument developers advancing the technique.

Welcome to “Analytically Speaking,” the podcast from LCGC International and Spectroscopy. In this episode, podcast co-hosts Dr. Dwight Stoll and Dr. James Grinias talk with Dr. Mark Schure, who has worked in separation science for over 35 years in both industry and academia. Over a 28-year period, he worked for Digital Equipment Corporation, the Rohm and Haas Company, and the Dow Chemical Company. Since then, he has served as Chief Technology Officer for Kroungold Analytical, and he has been an adjunct professor in the Department of Chemical and Biomolecular Engineering at the University of Delaware for over 20 years. Dr. Schure is a widely recognized expert in separation science who has published more than 110 papers, holds numerous patents, and edited the book Multidimensional Liquid Chromatography. His scientific interests encompass the fundamental separation science of complex molecules, polymers, and colloids, alongside 2D chromatography, retention mechanisms, and field flow fractionation. He has received numerous accolades, including the Eastern Analytical Symposium Award in Separation Science and the Uwe Neue Award from the HPLC conference. In a wide ranging conversation recorded live at the HPLC 2026 conference in Indianapolis following a memorial session for Prof. Peter Carr, we explore Mark’s unique entry into separation science, which benefited from prior experiences building amplifiers and electronics before transitioning to write Fortran software as a consultant for chemists at Northeastern University. We then discuss Mark’s foundational simulation work in field flow fractionation (FFF), including his approaches to modeling Coriolis effects and sedimentation. We also spend some time talking about Mark’s pioneering theoretical contributions to 2D chromatography on topics including sampling rate and detection limits. Finally, Mark shares his perspective on the intense inter-diffusion of information between his modeling group and Pete Carr and Ilja Siepmann at the University of Minnesota, the future of analytical chemistry, the need for improved analytical strategies for complex matrices like exosomes, and the potential for artificial intelligence to help identify unknown compounds in complex mixtures.

Infrared Reimagined: How FT-IR Spectroscopy Learned to Read Molecules, ©  Luis Eduardo  -chronicles-stock.adobe.com

FT-IR spectroscopy, long treated as a mature bench technique for confirming a carbonyl stretch or fingerprinting a polymer, has quietly become one of chemistry’s most versatile discovery engines: it now infers molecular structure straight from a spectrum without a reference library, resolves chemistry tens of nanometers wide, and screens a fingerstick of blood for disease in minutes. The last five years of published research show FT-IR moving from a confirmatory tool into a predictive, autonomous, and field-ready analytical platform.