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Rapid Analysis of Logging Wellhead Gases Based on Fourier Transform Infrared Spectroscopy

June 16th 2025

Fourier transform infrared (FT-IR) spectroscopy was used in this paper to rapidly analyze seven light alkanes (methane, ethane, propane, n-butane, i-butane, n-pentane, and i-pentane) in wellhead gases.

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Recognition of Process Degree for Gardeniae Fructus Praeparatus Based on Hyperspectral Data and Neural Network

June 10th 2025

Microscopic illustration of DNA double helix structure, highlighting gene silencing techniques with RNA interference, antisense oligonucleotides, for genetic research applications. Generated with AI. | Image Credit: © IQ-Photography - stock.adobe.com.
Quantification of Adenine Residues in the PolyA Tail of Oligonucleotides Using Raman Spectroscopy

June 5th 2025

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Research on Coal Classification Method Based on Terahertz Time-Domain Spectroscopy

May 28th 2025

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One-Step Green Synthesis of Functionalized Carbon Dots from Five Edible Mushrooms

May 23rd 2025

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Developing Portable Raman Spectroscopy Methods for Identification of Raw Materials Used in Pharmaceutical Development and Manufacturing

February 1st 2017

Portable instrumentation for Raman spectroscopy has rapidly evolved over the last decade, where sample testing that once occurred in the laboratory is now executed in the field (e.g. warehouse).   Portable Raman spectroscopy is a powerful technique for the rapid identification of diversely sourced raw materials used in pharmaceutical processing.  In addition to portability; reduced cost, rapid data acquisition and ease of use make this powerful technique attractive and accessible to both expert spectroscopists and non-specialists.  In most cases, the method development can be easily accomplished in the laboratory after which the instrument and methods are transferred to field for sample analysis or warehouse areas for inspection of incoming raw material.  Qualitative Raman methods for identification of raw materials typically utilize spectral libraries for sample to standard comparison.  When developing Raman spectral libraries for raw material identification, great care is required when considering critical factors (e.g. instrument type, Raman capability, container type, container interference, background interference, material variability) that can potentially influence the identity of the material.  This paper discusses portable Raman techniques and approaches for raw material identification, as well as key considerations for developing and validating Raman spectral libraries.