April 12th 2024
Here are the top five articles that the editors of Spectroscopy published this week.
The Role of Naturally Occurring Stable Isotopes in Mass Spectrometry, Part II: The Instrumentation
February 1st 2009In the second installment of this tutorial, the authors explain the instrumentation for measuring naturally occurring stable isotopes, specifically the magnetic sector mass spectrometer.
Liquid Matrices for Analyses by UV-MALDI Mass Spectrometry
August 7th 2008Data are presented for a pH-adjustable liquid UV-matrix-assisted laser desorption ionization (MALDI) matrix for mass spectrometry analysis. The liquid matrix system possesses high analytical sensitivity within the same order of magnitude as that achievable by the commonly used solid UV-MALDI matrices but with improved spot homogeneity and reproducibility. The pH of the matrix has been adjusted, achieving an on-target pH range of 3.5?8.6, which has allowed for the performance of a tryptic digest within the diluted pH-optimized liquid matrix.
Quantitative Mass Spectrometry Part III: An Overview of Regression Analysis
March 1st 2008Columnist Ken Busch presents the third of a five-part series on quantitative mass spectrometry. In this installment, he focuses on an overview of regression analysis for calibration lines and curves in mass spectrometry.