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A joint study between the Institute for Environment and Energy, Technology and Analytics (IUTA e. V., Duisburg, Germany) and Heinrich Heine University Düsseldorf (Germany) explored the combination of size exclusion chromatography (SEC) with diode array detector (DAD) and capillary-enhanced Raman spectroscopy (CERS) to directly analyze hemolyzed serum samples. We spoke to Jana Thissen, first author of the paper resulting from this study, about her team’s work.

Benjamin T. Manard has won the 2025 Emerging Leader in Atomic Spectroscopy Award for his pioneering research in nuclear material characterization and isotope ratio analysis, with expertise in advanced atomic spectrometry techniques such as inductively coupled plasma optical emission spectroscopy (ICP-OES), inductively coupled plasma mass spectrometry (ICP-MS), and laser ablation.

Hand holding a glowing AI sphere symbolizing the power and potential of artificial intelligence. | Image Credit: © lucegrafiar - stock.adobe.com.

This “Chemometrics in Spectroscopy” column traces the historical and technical development of these methods, emphasizing their application in calibrating spectrophotometers for predicting measured sample chemical or physical properties—particularly in near-infrared (NIR), infrared (IR), Raman, and atomic spectroscopy—and explores how AI and deep learning are reshaping the spectroscopic landscape.

Microscope image of modified DNA strands displayed on advanced digital equipment in a biotech lab. Generated with AI. | Image Credit: © Sukifli.D - stock.adobe.com.

In this column, I describe what I believe may be the origin of this fluorescence emission and support my conjecture with some measurements of polycyclic aromatic hydrocarbons (PAHs). Understanding the origin of these interfering backgrounds may enable you to design experiments with less interference, avoid the laser illuminations that make things worse, or both.

Foxtail millet | Image Credit: © zhengzaishanchu - stock.adobe.com.

The study developed an effective mid-infrared spectroscopic identification model, combining principal component analysis (PCA) and support vector machine (SVM), to accurately determine the geographical origin of five types of millet with a recognition accuracy of up to 99.2% for the training set and 98.3% for the prediction set.

Different citrus fruits as background, top view. | Image Credit: © New Africa - stock.adobe.com

Researchers from Jiangsu University review advancements in computer vision and spectroscopy for non-destructive citrus quality assessment, highlighting the role of AI, automation, and portable spectrometers in improving efficiency, accuracy, and accessibility in the citrus industry.

Orchid flower. | Image Credit: © phanthit malisuwan - stock.adobe.com

A new study published in Food Control combines Fourier transform infrared (FT-IR) spectroscopy and deep learning to accurately authenticate the geographical origin of Gastrodia elata f. glauca, offering a reliable method for geographical indication (GI) verification and fraud prevention in the herbal and food industry.

Female doctor using a microscope and examining glass beakers during research in a hospital laboratory, scientist working with modern technology in a clinical lab. Generated by AI. | Image Credit: © CinimaticWorks - stock.adobe.com

In celebration of the 2025 International Day of Women and Girls in Science, the editors of Spectroscopy highlight the work of women in analytical chemistry.

A recent study proposed a compact, cost-effective, handheld fiber-optic device using simplified DRS technology to track the accuracy of pedicle screw placement in spinal fusion procedures. Spectroscopy spoke to Merle Losch, corresponding author for the paper resulting from this study, about the device and the team’s efforts to produce it.

In a new study, a team of scientists used gel permeation chromatography, three-dimensional excitation-emission matrix fluorescence spectroscopy, and UV-visible spectroscopy to assess road runoff from drinking water treatment plants to evaluate the method' capacity for removing dissolved organic matter (DOM).