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Top articles published this week include a peer-reviewed article that discuss two multivariate calibration algorithms for the spectrophotometric analysis of a drug containing antazoline hydrochloride (AN) and naphazoline hydrochloride (NP), an article about chemometric calibrations, and a feature about the 2024 Emerging Leader in Molecular Spectroscopy awardee.

Spectrum of scattering for different wavelength of incident light. Generated by AI. | Image Credit: © BrilliantPixels - stock.adobe.com

In the second installment of “The Big Review,” we discuss the physical mechanism behind how molecules absorb infrared (IR) radiation. Because light can be thought of as a wave or a particle, we have two equivalent pictures of IR absorbance. We also discuss the quantum mechanics behind IR absorbance, and how this leads to the different peak types observed in IR spectrum.

Wave 3d. Wave of particles. Abstract Blue Geometric Background. Big data visualization. Data technology abstract futuristic illustration. 3d rendering. | Image Credit: © Vadym - stock.adobe.com

Data process mapping is an effective way to identify data integrity vulnerabilities and remediate them. A modified example published by the Active Pharmaceutical Ingredients Committee (APIC) is reviewed critically. Can it be simplified?