Over the past three to four years, Fourier Transform Infrared (FT-IR) spectroscopy has emerged as one of the most rapidly expanding vibrational techniques in biomedical research. Driven by advances in attenuated total reflectance (ATR), live-cell measurements, chemometrics, and machine learning (ML), FT-IR has moved beyond descriptive biochemical profiling toward predictive diagnostics and translational clinical science. This article highlights and critically summarizes the top 10 most influential peer-reviewed articles published recently on FT-IR applications in tissues, cells, hair, blood, saliva, urine, and exercise physiology, emphasizing analytical innovation, clinical relevance, and future impact.