Application Notes: General

• QuEChERS vs. a modified method with the Geno/Grinder for pesticide analysis • Stable isotope analysis for the testing of food product origins • Arsenic testing in hard ciders

• Achieving low detection limits by minimizing contamination in sample prep • Economic approach to reducing reagent blanks in ICP-OES and ICP-MS • Automated acid reflux cleaning system for maximum efficiency

• How to balance compliance needs with creating useful SOPs. • Tips and tricks for ensuring consistency. • Why and how you should test your SOPs

Reliable TOC analysis using the NPOC method with TIC control, high throughput by parallel purge and analysis, comparing catalytic combustion with UV-chemical oxidation.

This note looks at incidences of polymorphism in drug development including advantages and challenges.

• Raman spectroscopy of streamlining pharma QC and formulation development • Implementing transmission Raman for fast content uniformity testing • Through-container identity verification of polysorbates 20, 40, 60, and 80

• Even with a relatively light sample load of 250 samples per week, remeasuring 15% of them adds up to 2 weeks per year. • That’s 2 weeks you could be using for something more value-adding (and less boring).

Celldex utilized MMS to successfully observe the HOS of monoclonal antibody samples in complex buffer systems including excipients such as amino acids and sugars.

BSA samples analyzed at different concentrations to study heat induced thermal denaturation. Results show excellent reproducibility between sample replicates, concentrations.

Novel IR technique, microfluidic modulation spectroscopy, to address the requirements of development laboratories for high-quality higher-order structure assessment

This webinar presents a study mimicking the viral inactivation low pH hold used in purification of mAbs.

A new bioanalytical technique called microfluidic modulation spectroscopy is used to probe the backbone structure of IDE in the absence and presence of ATP and insulin.

This whitepaper explores MMS as a high-resolution method for the determination of protein HOS.

This webinar shows a demonstration of some of the key advantages of MMS for assessment of higher-order structure in therapeutic antibodies and antibody-drug conjugates.

An IgG1 sample was analyzed at different concentrations. The results in this poster from Pfizer, demonstrate high repeatability and precision of the diffAU spectra.

This application note provides insights for the transition of optical nanostructures from design to volume NIL manufacturing using wire grid polarizer as an example.

WITec Application Note: ParticleScout for Automated Confocal Raman Imaging Analysis of Microparticles

This application note demonstrates the performance of the company instrument for the analysis of semi volatiles based upon the specifications of USEPA method 8270D. This application note describes the importance of spectroscopy for the future of smart agriculture.

Many grains look alike - except in the NIR. See how easily a compact spectrometer and its OEM equivalent can distinguish a dozen grain types with some simple analysis.

This application note explores the analysis of legal cannabidiol using FTIR transmission spectroscopy.