Application Notes: General

Compositional depth profiles of hard disks were completed with the LECO GDS-850A. The first 50 nm revealed the elemental composition of the magnetic and nonmagnetic layers critical for their operation.

Milestone’s DMA-80 provides a highly flexible platform with an extremely wide dynamic detection range to analyze the different fish species with varying mercury levels.

Find out how Renishaw’s new inVia Qontor confocal Raman microscope can be used to acquire accurate and repeatable spectra from samples with extensive topographic variations.

Spectral Systems has developed its Diamond XP-BBAR™ coating with spectral performance. The SNR is about 30% better through most of the analysis region of a typical FT-IR instrument.

Black pepper is often subject to counterfeiting and adulteration. Creating elemental profiles for an individual spice can be used as a tool to identify possible adulteration.

The Agilent 5110 ICP-OES with Synchronous Vertical Dual View (SVDV) technology incorporates innovative hardware and software, allowing you to get better data faster, easier, and more cost effectively than ever before.

UVISEL ellipsometers have been used for the characterization of several systems of nanoparticles. This ellipsometric characterization involves the development of specific modeling tools available within DeltaPsi2 software.

Milestone’s UltraWAVE SRC benchtop microwave digestion enables cosmetic chemists to digest up to 15 different sample types simultaneously at temperatures as high as 300°C, greatly simplifying product development workflow with an easy efficient digestion sequence.

Photoluminescence and electroluminescence spectroscopy is a useful technique in the investigation of organic optoelectronic devices. The instrumentation for steady-state and time-resolved photoluminescence, as well as electroluminescence, is specified in this application note on organic solar cells.

Find out how the inVia confocal Raman microscope is used to conserve, study and analyse the precious ancient cultural relics from the Terracotta Warriors and Horses site.

It is vital to be able to rapidly and easily analyse the composition and structure of anodes. The inVia is ideal for locating, discriminating, and quantifying the different forms of carbon present in anodes, even those with subtle variations in structure.

The study of emulsions is important to provide information on interactions, separation, network connections and the role of emulsifiers. These are key to ensure emulsion is stable and suited to its specific role.

Learn why Renishaw’s inVia confocal Raman microscope is the ultimate system for studies ranging from fundamental research on the materials involved through to final product quality control and failure analysis.

The Agilent Multimode Sample Introduction System (MSIS) is an innovative option for both PerkinElmer Optima ICP-OES instruments and Agilent ICP-OES and Agilent MP-AES instruments. In this application note, we will show you how MSIS could help saves set-up and analysis time and also keep the lab as productive as possible.

The Milestone UltraWAVE can digest up to 22 different sample types simultaneously. The high temperature and pressure capability enables a complete digestion of nearly all inorganic sample types that need to be analyzed for trace metals.

Spectral Systems has developed Beamsplitter coating designs which offer the highest performance and eliminates undesirable spectral features.

Raman spectroscopy was used to control a semi-batch polymerization reaction. Kaiser Raman data enabled open-loop and closed-loop feedback control, allowing production of materials with consistent quality.

Mass Spectrometric Imaging (MSI) using DESI provides molecular imaging without the interference of the matrix required for MALDI and offers the advantage of preserving sample for further analysis. DESI coupled to High Resolution Accurate Mass (HRAM), is shown here to elucidate spatial distribution of lipids, protein, and metabolites in tissue sections and can provide confident and discriminate biomarker determinations.

Milestone’s DMA-80 provides a highly flexible platform with an extremely wide dynamic detection range to analyze coal samples with varying mercury levels.

PLIF, PIV and next generation imaging detectors - Combustion processes, if uncontrolled, are inherently inefficient and increasing the efficiency of combustion in engines, gas burners and furnaces is a significant challenge for the future due to limited fossil fuel resources and their effects on the environment.

Handheld Raman spectrometers are now designed and built for practical everyday use in a vast array of applications. The new BRAVO by Bruker takes handheld Raman Spectroscopy to a new level, overcoming the limitations of previously available systems such as limited wavelength accuracy, non-safe laser usage and fluorescence interference. Now with BRAVO wavelength accuracy is significantly better than competitive devices resulting in the highest data consistency and the BRAVO incorporates new technology called Sequentially Shifted Excitation (SSE™) to mitigate fluorescence.

A wireless NIR spectrometer is deployed on solid dose blending formulation for end-point monitoring. The MicroNIR PAT is democratizing the use NIR spectroscopy in pharmaceutical manufacturing facilitating Quality by Design (QbD) adoption.

This application note demonstrates the effectiveness of Agilent compact and portable FTIR systems for detecting counterfeit pharmaceuticals with three examples: ethambutol hydrochloride, cephuroxime axetil, and atorvastatin calcium.

This technical note describes features and functionality of Agilent MicroLab software (version 5.2 and later) in combination with SCM and SDA for data management and electronic traceability, which enable customers to implement the guidelines of 21 CFR Part 11.

This note highlights OpenLAB ECM Compliance Pack for UV-Vis Benefits such as efficient data storage and retrieval, security, data integrity and traceability, and 21 CFR Part II Comliance.

This note looks at specific components that require validation; the instrument, software, and validated test methods, and describes the features of the Agilent Cary 8454 UV-Visible system that is designed to meet the requirements of both initial and recurrent validation.

This note describes how the design of the Cary 8454 UV-Vis exceeds performance requirements stipulated by global pharmacopeia guidelines including USP and EP/BP. Configured for compliance, with 21 CFR Part 11, the instrument performs multi wavelength analysis, time-based kinetics assays, and routine QA/QC measurements.

This application note demonstrates how Agilent’s Cary 630 FTIR easily meets the specifications of the US, European, Japanese, Chinese, Indian and International Pharmacopoeia. Its combination of compact size, design, intuitive and regulation-compliant software makes the Cary 630 FTIR an ideal instrument for pharmaceutical quality control.