Application Notes: General

The study of emulsions is important to provide information on interactions, separation, network connections and the role of emulsifiers. These are key to ensure emulsion is stable and suited to its specific role.

Learn why Renishaw’s inVia confocal Raman microscope is the ultimate system for studies ranging from fundamental research on the materials involved through to final product quality control and failure analysis.

The Agilent Multimode Sample Introduction System (MSIS) is an innovative option for both PerkinElmer Optima ICP-OES instruments and Agilent ICP-OES and Agilent MP-AES instruments. In this application note, we will show you how MSIS could help saves set-up and analysis time and also keep the lab as productive as possible.

The Milestone UltraWAVE can digest up to 22 different sample types simultaneously. The high temperature and pressure capability enables a complete digestion of nearly all inorganic sample types that need to be analyzed for trace metals.

Spectral Systems has developed Beamsplitter coating designs which offer the highest performance and eliminates undesirable spectral features.

Raman spectroscopy was used to control a semi-batch polymerization reaction. Kaiser Raman data enabled open-loop and closed-loop feedback control, allowing production of materials with consistent quality.

Mass Spectrometric Imaging (MSI) using DESI provides molecular imaging without the interference of the matrix required for MALDI and offers the advantage of preserving sample for further analysis. DESI coupled to High Resolution Accurate Mass (HRAM), is shown here to elucidate spatial distribution of lipids, protein, and metabolites in tissue sections and can provide confident and discriminate biomarker determinations.

Milestone’s DMA-80 provides a highly flexible platform with an extremely wide dynamic detection range to analyze coal samples with varying mercury levels.

PLIF, PIV and next generation imaging detectors - Combustion processes, if uncontrolled, are inherently inefficient and increasing the efficiency of combustion in engines, gas burners and furnaces is a significant challenge for the future due to limited fossil fuel resources and their effects on the environment.

A wireless NIR spectrometer is deployed on solid dose blending formulation for end-point monitoring. The MicroNIR PAT is democratizing the use NIR spectroscopy in pharmaceutical manufacturing facilitating Quality by Design (QbD) adoption.

This application note demonstrates the effectiveness of Agilent compact and portable FTIR systems for detecting counterfeit pharmaceuticals with three examples: ethambutol hydrochloride, cephuroxime axetil, and atorvastatin calcium.

This technical note describes features and functionality of Agilent MicroLab software (version 5.2 and later) in combination with SCM and SDA for data management and electronic traceability, which enable customers to implement the guidelines of 21 CFR Part 11.

This note highlights OpenLAB ECM Compliance Pack for UV-Vis Benefits such as efficient data storage and retrieval, security, data integrity and traceability, and 21 CFR Part II Comliance.

This note looks at specific components that require validation; the instrument, software, and validated test methods, and describes the features of the Agilent Cary 8454 UV-Visible system that is designed to meet the requirements of both initial and recurrent validation.

This note describes how the design of the Cary 8454 UV-Vis exceeds performance requirements stipulated by global pharmacopeia guidelines including USP and EP/BP. Configured for compliance, with 21 CFR Part 11, the instrument performs multi wavelength analysis, time-based kinetics assays, and routine QA/QC measurements.

This application note demonstrates how Agilent’s Cary 630 FTIR easily meets the specifications of the US, European, Japanese, Chinese, Indian and International Pharmacopoeia. Its combination of compact size, design, intuitive and regulation-compliant software makes the Cary 630 FTIR an ideal instrument for pharmaceutical quality control.

The Agilent Cary 8454 UV-Visible system is ideal for regulatory Pharma QA/QC applications, and can acquire a complete spectrum in less than 1 second. This technical note outlines both applications-based and technical considerations for choosing a diode array UV-Vis

This application note describes a very sensitive classification method, partial least squares–discriminant analysis (PLS-DA), incorporated in Agilent innovative MicroLab software, to classify and qualify materials of interest with greater sensitivity and specificity than possible with simple library search methods.

Photoluminescence (PL) lifetime measurements in NIR are the key parameters in assessing the optical efficiency of devices involving lanthanides, as well as in quality control during their manufacturing.

PFA cyclonic spray chamber was evaluated for use with a Thermo ElementXR HR-ICP-MS. The signal stability of the cyclonic spray chamber was studied, along with its washout.

Understand how specific design features achieve extreme matrix tolerance and chemical inertness combined with high sensitivity and precision.

Reliability of a low flow glass concentric nebulizer combines with chemical resistance and low elemental background of a PFA concentric nebulizer.

FT-IR microscopy constitutes a very fast and efficient alternative to the well-established staining methods. It allows to analyze biological samples with minimal sample preparation and without the need for any agents for contrast enhancement.

Analysis of trace elements in petrochemical samples is routinely carried out for quality control and process monitoring using protocols set by organizations such as ASTM. However, analysis of these samples is often challenging due to the high matrix and potential for interferences. This executive summary will provide essential information on how to develop robust methods over coming these challenges and ensure excellent results when analyzing trace elements in petrochemicals samples by ICP-OES.

The Milestone UltraWAVE is a bench-top instrument that operates at very high pressures and temperatures, capable of processing large, dissimilar and difficult samples quickly, easily-all without batching. The data shown in this technical note demonstrates that the digestion of samples in the UltraWAVE results in uniformly high analytical data quality, making it the ideal solution for trace metals detection in food.

BaySpec’s PeakFinderTM Raman video probe combines a flexible fiber optic probe with microscope objectives allowing sampling down to several microns. Combined with various benchtop Raman spectrometers, the Raman video probe is a unique micro-Raman system available in 532, 785 or 1064nm excitation and various microscope objectives offering unprecedented flexibility and versatility.

Raman spectroscopy is an important instrument in the arsenal of art conservators and archaeologists. This application note summarizes some recent literature on the selection of portable instruments in this field and also documents some successful work done utilizing background correction to elucidate the composition of some challenging green pigments.