Machine Learning Accelerates Clinical Progress of SERS Technology
May 22nd 2025A new review in TrAC Trends in Analytical Chemistry by Alfred Chin Yen Tay and Liang Wang highlights how machine learning (ML) is transforming surface-enhanced Raman spectroscopy (SERS) into a powerful, clinically viable tool for rapid and accurate medical diagnostics.
Fluorescence Spectroscopy Emerges as Rapid Screening Tool for Groundwater Contamination in Denmark
May 21st 2025A study published in Chemosphere by researchers at the Technical University of Denmark demonstrates that fluorescence spectroscopy can serve as a rapid, on-site screening tool for detecting pharmaceutical contaminants in groundwater.
China Institutions Team Up to Oxidize Toluene at Lower Temperatures
May 21st 2025Researchers from several Chinese universities have developed a low-cost, red mud-based catalyst doped with manganese oxides that efficiently oxidizes toluene at lower temperatures, offering a sustainable solution for air pollution control and industrial waste reuse.
The Future of Neurodegenerative Disease Research and the Role of IR Imaging
May 21st 2025In the final part of this three-part interview, Ayanjeet Ghosh of the University of Alabama and Rohit Bhargava of the University of Illinois Urbana-Champaign talk about the key performance metrics they used to evaluate their model, and what the future of neurodegenerative disease research looks like.
Whey Protein Fraud: How Portable NIR Spectroscopy and AI Can Combat This Issue
May 20th 2025Researchers from Tsinghua and Hainan Universities have developed a portable, non-destructive method using NIR spectroscopy, hyperspectral imaging, and machine learning to accurately assess the quality and detect adulteration in whey protein supplements.
Describing Their Two-Step Neural Model: An Interview with Ayanjeet Ghosh and Rohit Bhargava
May 20th 2025In the second part of this three-part interview, Ayanjeet Ghosh of the University of Alabama and Rohit Bhargava of the University of Illinois Urbana-Champaign discuss how machine learning (ML) is used in data analysis and go into more detail about the model they developed in their study.
Analyzing the Protein Secondary Structure in Tissue Specimens
May 19th 2025In the first part of this three-part interview, Ayanjeet Ghosh of the University of Alabama and Rohit Bhargava of the University of Illinois Urbana-Champaign discuss their interest in using discrete frequency infrared (IR) imaging to analyze protein secondary structures.
Best of the Week: Recognizing Albert A. Michelson, Studying Star Clusters, Elemental Analysis
May 16th 2025Top articles published this week include a new Icons of Spectroscopy column, a news story about the use of Fourier transform infrared (FT-IR) spectroscopy in gemology, and a Q&A interview about elemental analysis in pharmaceutical analysis.
How Do We Improve Elemental Impurity Analysis in Pharmaceutical Quality Control?
May 16th 2025In this final part of our conversation with Harrington and Seibert, they discuss the main challenges that they encountered in their study and how we can improve elemental impurity analysis in pharmaceutical quality control.
Accurate Plastic Blend Analysis Using Mid-Infrared Spectroscopy
May 15th 2025Researchers at the Sinopec Research Institute have developed a novel method using virtually generated mid-infrared spectra to accurately quantify plastic blends, offering a faster, scalable solution for recycling and environmental monitoring.
How do Pharmaceutical Laboratories Approach Elemental Impurity Analysis?
May 14th 2025Spectroscopy sat down with James Harrington of Research Triangle Institute (RTI International) in Research Triangle Park, North Carolina, who was the lead author of this study, as well as coauthor Donna Seibert of Kalamazoo, Michigan. In Part I of our conversation with Harrington and Seibert, they discuss the impact of ICH Q3D and United States Pharmacopeia (USP) <232>/<233> guidelines on elemental impurity analysis and how they designed their study.
Exploring Data Transforms in Chemometrics
May 14th 2025Our “Chemometrics in Spectroscopy” column highlights the methodology that is used in order to apply chemometric methods to data. Integrating chemometrics with spectroscopy allows scientists to understand solutions to their problems when they encounter surprising results. Recently, columnists Howard Mark and Jerome Workman, Jr., wrote a series of articles about data transforms in chemometric calibrations. In this listicle, we profile all pieces in this series and invite you to learn more about applying chemometric models to continuous spectral data.
New SERS Platform Enhances Real-Time Detection of Cardiovascular Drugs in Blood
May 13th 2025Researchers at Harbin Medical University recently developed a SERS-based diagnostic platform that uses DNA-driven “molecular hooks” and AI analysis to enable real-time detection of cardiovascular drugs in blood while eliminating interference from larger biomolecules.
Best of the Week: Hawaii’s Hidden Geology, Waters Announces Software Update
May 9th 2025Top articles published this week include an announcement from Waters Corporation, a news story about the hidden geology of the Big Island of Hawaii, the latest “IR Spectral Interpretation” column, which focuses on analyzing carbonyl compounds, and wearable spectroscopy sensors.
Using Spectroscopy to Understand Hawaii’s Hidden Geology
May 8th 2025Researchers from the University of Nevada, Reno, have conducted the most comprehensive subsurface analysis of Hawaiian shield basalts to date, using advanced spectroscopic and geochemical techniques to reveal short-lived hydrothermal alteration processes and establish a new foundation for future volcanic and geothermal studies.
Inside the Laboratory: The Weker Group at SLAC National Accelerator Laboratory, Part IV
May 6th 2025In this edition of “Inside the Laboratory,” Johanna Nelson Weker of SLAC National Accelerator Laboratory discusses her laboratory’s work in battery analysis. In the final part of our interview, Weker continues our discussion of battery cell geometries and why computed laminography is a good technique to use for this purpose.
New Imaging Method Offers Breakthrough in Forest Soil and Tree Analysis
May 5th 2025A new study published in Geoderma Regional by J. A. Arias-Rios and colleagues at IFAB demonstrates that near-infrared (NIR) spectroscopy is a rapid, cost-effective tool for assessing soil and tree traits critical to forest ecosystem monitoring and management.