Raman Spectroscopy

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AI-powered SERS boosts safety of medicinal food products © Udomner-chronicles-stock.adobe.com
AI-Powered SERS Spectroscopy Breakthrough Boosts Safety of Medicinal Food Products

April 16th 2025

A new deep learning-enhanced spectroscopic platform—SERSome—developed by researchers in China and Finland, identifies medicinal and edible homologs (MEHs) with 98% accuracy. This innovation could revolutionize safety and quality control in the growing MEH market.

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New Study Reveals Insights into Phenol’s Behavior in Ice

April 16th 2025

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New Raman Spectroscopy Method Enhances Real-Time Monitoring Across Fermentation Processes

April 15th 2025

AI-driven Raman spectroscopy for precision cancer immunotherapy © freshidea-chronicles-stock.adobe.com
AI-Driven Raman Spectroscopy Paves the Way for Precision Cancer Immunotherapy

April 15th 2025

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New Aluminum Microwell Platform Improves Single-Cell Raman Spectroscopy for Cancer Research

April 14th 2025

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Recording the Raman Spectrum of a Single Molecule

Recording the Raman Spectrum of a Single Molecule

September 2nd 2021

Analytical chemists are continually striving to advance techniques to make it possible to observe and measure matter and processes at smaller and smaller scales. Professor Vartkess Ara Apkarian and his team at the University of California, Irvine have made a significant breakthrough in this quest: They have recorded the Raman spectrum of a single azobenzene thiol molecule. The approach, which breaks common tenets about surface-enhanced Raman scattering/spectroscopy (SERS) and tip-enhanced Raman spectroscopy (TERS), involved imaging an isolated azobenzene thiol molecule on an atomically flat gold surface, then picking it up and recording its Raman spectrum using an electrochemically etched silver tip, in an ultrahigh vacuum cryogenic scanning tunneling microscope. For the resulting paper detailing the effort [1], Apkarian and his associates are the 2021 recipients of the William F. Meggers Award, given annually by the Society for Applied Spectroscopy to the authors of the outstanding paper appearing in the journal Applied Spectroscopy. We spoke to Apkarian about this research, and what being awarded this honor means to him and his team. This interview is part of an ongoing series with the winners of awards that are presented at the annual SciX conference. The award will be presented to Apkarian at this fall’s event, which will be held in person in Providence, Rhode Island, September 28–October 1.