Raman Spectroscopy

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New Raman Spectroscopy Method Boosts Drug Component Detection Accuracy and Speed

May 23rd 2025

Researchers at Guangdong University of Technology have developed a fast, non-destructive Raman spectroscopy method to accurately detect active ingredients in complex drug formulations.

An example of a cave painting. | Image Credit: © R.M. Nunes - stock.adobe.com
Multi-Analytical Study Reveals Complex History Behind Ancient Snake Motif in Argentine Rock Art

May 22nd 2025

Mineral identification using AI and Raman spectroscopy © Joriah-chronicles-stock.adobe.com
New Deep Learning AI Tool Decodes Minerals with Raman Spectroscopy

May 21st 2025

Transforming THz spectroscopy into mining data © Shutter2U-chronicles-stock.adobe.com
How THz and THz-Raman Spectroscopy Are Used in Drug Safety, Farming, and Mining

May 20th 2025

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Recording the Raman Spectrum of a Single Molecule

Recording the Raman Spectrum of a Single Molecule

September 2nd 2021

Analytical chemists are continually striving to advance techniques to make it possible to observe and measure matter and processes at smaller and smaller scales. Professor Vartkess Ara Apkarian and his team at the University of California, Irvine have made a significant breakthrough in this quest: They have recorded the Raman spectrum of a single azobenzene thiol molecule. The approach, which breaks common tenets about surface-enhanced Raman scattering/spectroscopy (SERS) and tip-enhanced Raman spectroscopy (TERS), involved imaging an isolated azobenzene thiol molecule on an atomically flat gold surface, then picking it up and recording its Raman spectrum using an electrochemically etched silver tip, in an ultrahigh vacuum cryogenic scanning tunneling microscope. For the resulting paper detailing the effort [1], Apkarian and his associates are the 2021 recipients of the William F. Meggers Award, given annually by the Society for Applied Spectroscopy to the authors of the outstanding paper appearing in the journal Applied Spectroscopy. We spoke to Apkarian about this research, and what being awarded this honor means to him and his team. This interview is part of an ongoing series with the winners of awards that are presented at the annual SciX conference. The award will be presented to Apkarian at this fall’s event, which will be held in person in Providence, Rhode Island, September 28–October 1.