Application Notes

Fluorescence spectroscopy is used to investigate museum specimen as a flexible and minimally invasive technique. The photo-physical properties of Egyptian and modern artwork pigments are presented in this application note.

The cost of poor quality data in nucleic acid or protein work cannot be underestimated yet for some reason is overlooked. This note investigates a simple solution to the problem.

The characterization of the active pharmaceutical ingredient (API) and its distribution and physical properties in commercial medicine is necessary in drug research and development process in the pharmaceutical industry. Among various analytical techniques employed for this purpose, Raman spectroscopy is gaining more popularity due to its advantages as non-destructive, non-invasive, fast spectrum acquisition in seconds, high reproducibility, and so on.

Miniature X-ray sources reached the development level that is appropriate for their use in the hand held and portable X-Ray diffraction (XRD) instruments. This note describes the application of X-ray sources for the residual stress measurements using XRD.

Protein secondary structure during thermal unfolding and aggregation is readily acquired using IR spectroscopy and a temperature-controlled mid-IR transmission accessory. Myoglobin was used as a model system to illustrate the method.

To learn more about Method development for ICP-OES, Spectroscopy Magazine talked with Matthew Cassap, Product Manager ICP-OES, AA, and Trace Elemental Analysis at Thermo Fisher Scientific.

Introducing a new single quadrupole ICP-MS to the range of trace elemental analysis solutions offered by Thermo Scientific. To learn more, Spectroscopy Magazine talked with Shona McSheehy-Ducos, ICP-MS Product Manager, Thermo Fisher Scientific in Bremen, Germany.

Here we demonstrate how PerkinElmer’s PinAAcle™ 900 atomic absorption spectrometer coupled to a FAST Flame sample automation accessory can analyze common nutritional elements in fortified cereals.

Moxtek’s PBS products enable engineers the flexibility to design optical systems optimized for performance, size, and weight for use in projection display, virtual and augmented reality HMD, and HUD systems.

Overcoming the boundary between user-friendliness and the ultimate capability in Raman Imaging is the key to effortlessly manage the image-acquisition and data evaluation at the highest lateral and spectral resolution. This executive summary will explore how the most intricate Raman Imaging experiments can be easily accomplished leading to a greatly improved data quality, ease of use and productivity.

Optimization and follow up of manufacturing process of plastics films are easily achieved using Pulsed RF Glow Discharge Optical Emission Spectrometry. This technique allows the fast detection of defects and presence of contaminants.

Combining SPRi technology with MALDI mass spectrometry on the same surface is a powerful approach for the analysis of biomolecular interactions, allowing measurement of biomolecular interactions by SPRi, and then detection of the retained ligands by MALDI mass spectrometry directly from the sensor surface.

This appnote shows the benefits of using pulsed RF GDOES for the analysis of films containing nanoparticles

This appnote shows the application of GDOES to materials used in Solid Oxide Fuel Cells, which are based on chemical oxidation of the fuel rather than its combustion, offering high efficiency without forming air pollutants.

Raman spectroscopy has been used to analyze the process of micro-encapsulation of flavors. This contribution shows the example of distribution of limonene and quantification of its content within the micro-particles.

During the charging and discharging process, lithium ions travel from one electrode to another. This application note explains how Raman Spectroscopy can be helpful in the analysis of cathodes and anodes for R&D and QC.

Surface Plasmon Resonance (SPR) is an optical technique that offers label-free biomolecular analyses, providing information on kinetic processes (association and dissociation), binding affinity, analyte concentration and real time molecule detection. It has become a powerful tool for the analysis of biomolecular events involved in drug development, cancer research, and antibody screening

Exposure to warm/humid conditions may cause pharmaceutical formulations to undergo change in hydration level, affecting properties and/or efficiency of the drug. Raman spectroscopy, with a temperature and humidity controller can mimic harsh conditions, monitor properties of ingredients and track modifications induced by environmental changes.

Time‐resolved Fluorescence can analyze potential health benefits from antioxidant activity of curcumin, found in turmeric. Curcuminoids, weakly fluorescent in aqueous solution, show quantum yield increases upon interaction with a protein, such as human serum albumin.

Locate particles, generate size/shape statistics, select particles based on size/shape, and acquire Raman spectra. Easily locate and identify particulate matter, including pharmaceutical materials, trace forensic evidence, geological rock/mineral particles, and airborne contaminants trapped on filters

Since the function of a protein is closely related to its structure, the structural analysis of proteins and peptides is becoming increasingly important to assist in deciphering bioactivity. CD measurements are easy to obtain, and small sample volumes can be used. Additionally, conformational changes of proteins and peptides due to pH, temperature and external ligands can also be obtained.

Alpha includes a teaching kit with comprehensive set of tools for universities and vocational schools to demonstrate and explain the application of FT-IR spectroscopy. Comes with starter package of different measurement accessories, wizard guided user interface and detailed instruction manual

The step-scan technique allows the monitoring of the temporal progress of very fast reproducible events (transients). The interferometer mirror consecutively steps to the separate interferogram points one by one where the experiment is restarted again

IR and Raman spectroscopy are powerful analytical techniques to detect, discriminate and identify material on a molecular level. Raman spectroscopy offers some advantages when applied to art and archaeology as well as earth sciences.

Advanced analytical methods and techniques for food control can help to safeguard human health and even lives. Bruker offers a comprehensive range of lab-based and in-situ solutions to detect and diagnose potential and existing threats and contaminations at any stage

Protein secondary structure during thermal unfolding and aggregation is readily acquired using IR spectroscopy and a temperature-controlled Mid-IR transmission accessory.

Patented UltraWAVE SRC technology goes beyond traditional digestion, offering greater capabilities for the most difficult sample types. High-performance stainless steel construction allows for higher pressures and temperatures, while disposable vessels eliminate the need to assemble, disassemble or clean between processing. Just as important, dissimilar samples can be processed simultaneously, saving time and money.

Up-conversion finds important applications from biological labels to sensors and solar cells. This application note elucidates the experimental requirements for the characterisation of up-conversion using lanthanides as a model material.

The combination of fast, modular spectrometers from Ocean Optics, with powerful chemometrics tools creates new opportunities for rapid, on-site testing of foods and other samples. From quick and inexpensive measurements in complex situations, to sample identification rivaling expert abilities or online quality control – the possibilities are endless.

Test new and used motor and hydraulic oils with the new liquid transmission analysis essential from Specac, the PearlTM.