Application Notes: General

The purification of oligonucleotides (ONs) can be particularly challenging because of the high similarity of target and impurities.

The urgency caused by the SARS-CoV-2 pandemic of 2020 prompted policy makers and pharmaceutical firms alike to develop and deploy mRNA vaccines with unprecedented speed.

To demonstrate the suitability of ICP-OES for fast, sensitive, and robust analysis of elements in water samples, following the DIN EN ISO 11885:2009 requirements.

Glass Expansion’s Peltier Cooled Cyclonic (PCC) Spray Chamber Kit is fully compatible with the Agilent® 7900 and 8900, and with the legacy Agilent® ICP-MS models.

This application note is about tracking polymorph and crystal morphology using non-invasive in situ analysis at small scale.

LECO’s GDS instruments are ideal for investigating PVD coatings and the factors that determine their protection of substrate, as shown by this application note.

Learn how to select the most appropriate microwave digestion technology for determining trace and heavy metals via ICP-OES and ICP-MS.

Here, we explore the benefits of using a multiple reflection, variable angle attenuated total reflectance (ATR) instrument to generate the most informative spectral data. c

Brochure highlights Ocean Insight’s application capabilities, with examples from characterization of paint properties to monitoring of lens material curing processes.

The spectral and time-resolved X-ray-excited luminescence of a liquid scintillator is studied using an Edinburgh photoluminescence spectrometer and X-ray sample chamber.

Nicro, Endress+Hauser, and BIOCentre worked together to create a safe, in-line bioprocess control solution with real-time monitoring.

Using Analytik Jena’s iCRC technology for interference removal, we demonstrate the measurement of 82 drinking water samples per h with 21 elements (+4 internal standards).

Discover how to acquire reproducible and reliable determination of total organic carbon (TOC) content in drinking water providing a high inorganic-carbon matrix.

The determination of mercury concentrations in environmental samples such as natural waters and wastewaters is important in environmental risk assessment.

Analytik Jena’s high-resolution ICP-OES with high sensitivity complies with concentration limits of drinking water regulations with no requirement of further accessories.

A species-unspecific response of high-resolution continuum source graphite furnace molecular absorption was developed for the determination of a sum parameter of fluorinated compounds.

Therapeutic proteins have been explored for their use in cancer treatment, autoimmune disease, and other difficult-to-treat conditions. But, their stability is critical for patient safety and efficacy. This ebook on FTIR/NIR/Raman in Bio/Pharmaceutical Analysis discusses some common techniques used for evaluated the physical stability and activity of biologics.

The world’s smartest palm spectrometer for 400–2500 nm operates using one-button. Miniaturized optics make it highly efficient for maximum sensitivity with ultrafast acquisition.

This survey shows how Raman imaging can characterize food samples such as honey, chocolate, and fat spreads to help understand the products and production processes.  

In this application note, we discuss the implementation of offset phase locking using a digital phasemeter, and characterize the stability of phase locking two lasers.

This application note demonstrates the performance for the measurement of sulfur in ultra-low sulfur diesel using full polarization in 90° Cartesian geometry EDXRF.

In this application, the rapid scan rate of the Ocean FX spectrometer enables measurement of flicker (frequency, amplitude, chromatic variation) in home lighting.

Infrared reflection-absorption spectroscopy (IRRAS) is a powerful tool for the structural analysis of monolayers at the air/water interface.

Through-the-vial analytical capabilities for real-time Raman combined with accurate temperature-controlled parallel crystallizer with transmissivity measurement

This white paper describes applications of cryoRaman, a cryogenic Raman microscope offering VIS to NIR excitation, high magnetic fields, and full polarization control.

Combining imaging with broadband spectroscopy provides spatiospectral nanoimaging of 2D materials with nanometer spatial resolution and wide spectral coverage.

Since antigens used in pharmaceutical vaccine production typically consist of proteins, the analytical quantification of total protein is a method of choice.