May 2nd 2025
In this extended Q&A interview, we sit down with Kelsey Williams, a postdoctoral researcher at Los Alamos National Laboratory (LANL), who is working on planetary instrumentation using spectroscopic techniques such as laser-induced breakdown spectroscopy (LIBS) and laser ablation molecular isotopic spectrometry (LAMIS). In the final part of our conversation with Williams, she discusses how laser-based spectroscopic techniques might be used in the future to advance space exploration.
Using NIR Spectroscopy as an Integrated PAT Tool (PDF)
December 1st 2004This article summarizes recent efforts by the Duquesne University Center for Pharmaceutical Technology to develop and validate a PAT method using NIR spectroscopy for the on-line prediction of tablet hardness and active pharmaceutical ingredient content.
Using NIR Spectroscopy as an Integrated PAT Tool (PDF)
December 1st 2004This article summarizes recent efforts by the Duquesne University Center for Pharmaceutical Technology to develop and validate a PAT method using NIR spectroscopy for the on-line prediction of tablet hardness and active pharmaceutical ingredient content.
Masses in Mass Spectrometry: Balancing the Analytical Scales (PDF)
November 1st 2004Mass spectrometrists have been measuring masses in the ultrasmall world for the past 50 years. However, a sense of our own accomplishments does not derive from the same perspective linking ultrasmall masses to the normal-mass world.
Depth Profiling with Confocal Raman Microscopy, Part II (PDF)
November 1st 2004Part II of the two-part series continues the discussion on the interpretation of confocal Raman data, including how depth resolution is degraded when focusing deep within a sample and how intensity variations can occur when focusing near a sample's surface.
Strategies for Higher Throughput MS Analyses (PDF)
November 1st 2004The authors discuss current approaches for increasing throughput in MS analyses, including improved software information flow, data management and effective sample preparation, and how researchers should consider each of these with regard to their own needs.
Fast Multidimensional NMR Spectroscopy by the Projection-Reconstruction Technique (PDF)
October 1st 2004The authors describe a new method for making faster measurements of multidimensional NMR spectra. The technique involves acquiring a small number of projections and using them to reconstruct the entire spectrum.
Depth Profiling With Confocal Raman Microscopy, Part I (PDF)
October 1st 2004Raman microscopy is one of the techniques of choice for investigating heterogeneous systems on the micrometer scale. Part I of this two-part article series reviews the issues that must be considered to interpret confocal Raman data correctly.