December 4th 2024
Spectroscopy spoke with Uwe Karst, a full professor at the University of Münster in the Institute of Inorganic and Analytical Chemistry, to discuss his research on hyphenated analytical techniques in battery research.
November 27th 2024
Raman Microscopy as a Valuable Tool for Failure Analysis (PDF)
June 2nd 2004The authors discuss several sample types encountered in their laboratory for which Raman spectroscopy is the only reliable method of analysis. The technique is shown to be a routine and cost-effective tool for the industrial laboratory.
Raman Spectroscopy for Homeland Defense Applications (PDF)
June 2nd 2004Raman spectroscopy is used routinely by the agencies tasked with homeland defense, and current research using surface enhanced Raman spectroscopy shows promise for the detection of chemical warfare agents and other toxic chemicals. This article overviews some of the latest developments in the field.
Recent Advances in Bioanalytical Mass Spectrometry and Their Application to Marine Toxins (PDF)
June 1st 2004The analytical challenges in marine chemistry are numerous due to the large number of natural toxins and their metabolites, the highly toxic nature of many of these compounds, and increasingly stringent regulatory guidelines. This article gives an overview of some recently developed mass spectrometry techniques and their application to marine biotoxins.
TLC-MALDI in Pharmaceutical Analysis (PDF)
April 29th 2004Thin-layer chromatography (TLC) is a widely used technique for the rapid examination of compound purity. The amount of qualitative information, however, is limited to the retention factor of compounds. The technique described here enables the direct determination of TLC plates by MALDI MS.
Versatile Protein Identification Using AP-MALDI Ion Trap Mass Spectrometry (PDF)
April 29th 2004New developments in matrix-assisted laser desorption ionization (MALDI) technology enable decoupling of the ionization source from the time-of-flight mass analyzer for operation at atmospheric pressure (AP-MALDI). This technique also can be integrated with other types of mass analyzers, such as the ion trap.
Tautomerism and Expert Systems in Spectroscopy (PDF)
April 1st 2004Because tautomers often cannot be isolated as single isomers, spectroscopists should always anticipate possible tatomeric forms that can complicate the interpretation of their spectra. This involves the use of spectral databases and tautomerically enabled search algorithms.
The authors discuss progress in near-field IR microspectroscopy using a photothermal probe and show how it can be applied to the spectroscopic characterization of real-world samples.
The authors discuss progress in near-field IR microspectroscopy using a photothermal probe and show how it can be applied to the spectroscopic characterization of real-world samples.