July 17th 2025
Researchers at China’s National Key Laboratory have identified 170 nickel autoionization states using resonance ionization mass spectrometry, significantly advancing the spectral database critical for laser isotope separation and atomic spectroscopy.
FT-IR Spectroscopy: An Advanced Tool for Studying Biomedical Problems (PDF)
July 1st 2004The authors describe several applications of FT-IR spectroscopy in the biomedical sciences, including characterization of healthy and neoplastic human skin samples affected by two kinds of cancers, and examination of liver damage and regeneration caused by carbon tetrachloride.
Powerful Partners Provide Complete Analytical Solutions (PDF)
June 2nd 2004This article examines advances that have been made to combine existing analytical techniques with Raman instrumentation. Some of these methods offer enhanced sample visualization, while others provide complementary vibrational spectroscopic information from a single sample point.
Raman Microscopy as a Valuable Tool for Failure Analysis (PDF)
June 2nd 2004The authors discuss several sample types encountered in their laboratory for which Raman spectroscopy is the only reliable method of analysis. The technique is shown to be a routine and cost-effective tool for the industrial laboratory.
Raman Spectroscopy for Homeland Defense Applications (PDF)
June 2nd 2004Raman spectroscopy is used routinely by the agencies tasked with homeland defense, and current research using surface enhanced Raman spectroscopy shows promise for the detection of chemical warfare agents and other toxic chemicals. This article overviews some of the latest developments in the field.
Recent Advances in Bioanalytical Mass Spectrometry and Their Application to Marine Toxins (PDF)
June 1st 2004The analytical challenges in marine chemistry are numerous due to the large number of natural toxins and their metabolites, the highly toxic nature of many of these compounds, and increasingly stringent regulatory guidelines. This article gives an overview of some recently developed mass spectrometry techniques and their application to marine biotoxins.
TLC-MALDI in Pharmaceutical Analysis (PDF)
April 29th 2004Thin-layer chromatography (TLC) is a widely used technique for the rapid examination of compound purity. The amount of qualitative information, however, is limited to the retention factor of compounds. The technique described here enables the direct determination of TLC plates by MALDI MS.
Versatile Protein Identification Using AP-MALDI Ion Trap Mass Spectrometry (PDF)
April 29th 2004New developments in matrix-assisted laser desorption ionization (MALDI) technology enable decoupling of the ionization source from the time-of-flight mass analyzer for operation at atmospheric pressure (AP-MALDI). This technique also can be integrated with other types of mass analyzers, such as the ion trap.